Evidence map›Paper›PMID 32317144›Full record

ReviewSeminars in cell & developmental biology2020

Direct trafficking pathways from the Golgi apparatus to the plasma membrane.

Danièle Stalder, David C Gershlick

Open access · greenAbstract readReview
In one paragraph

Review in Seminars in cell & developmental biology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 82 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
82citing papers in PubMed, 1 pooled it
8.6field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

82 citing papers in PubMed, 1 synthesis or guideline pooled it, 156 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Volumetric Single-Molecule Tracking Inside Subcellular Structures.Small (Weinheim an der Bergstrasse, Germany) · 2026
    Article
  8. Review
  9. A class of COPI cargo receptors regulates processing of transmembrane proteins by reinforcing their Golgi retention.Proceedings of the National Academy of Sciences of the United States of America · 2026
    Article
  10. Article
  11. Review
  12. Article
  13. Review
  14. Review
  15. Article
  16. Review
  17. Review
  18. Proteostasis of immune checkpoint receptors.The Biochemical journal · 2025
    Review
  19. Article
  20. Electrical Stimulation Therapy - Dedicated to the Perfect Plastic Repair.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025
    Review

22 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Danièle StalderCambridge Institute for Medical Research, University of Cambridge, Cambridge, United Kingdom.
David C GershlickCambridge Institute for Medical Research, University of Cambridge, Cambridge, United Kingdom. Electronic address: dg553@cam.ac.uk.
University of Cambridge · GB

Funding

Wellcome Trust 210481/Z/18/Z
6 · The paper itself

Abstract

In eukaryotic cells, protein sorting is a highly regulated mechanism important for many physiological events. After synthesis in the endoplasmic reticulum and trafficking to the Golgi apparatus, proteins sort to many different cellular destinations including the endolysosomal system and the extracellular space. Secreted proteins need to be delivered directly to the cell surface. Sorting of secreted proteins from the Golgi apparatus has been a topic of interest for over thirty years, yet there is still no clear understanding of the machinery that forms the post-Golgi carriers. Most evidence points to these post-Golgi carriers being tubular pleomorphic structures that bud from the

Indexed as

AnimalsCell MembraneGolgi ApparatusHumansLipid MetabolismMembrane FusionProtein TransportSecretory PathwayATP, adenosine triphosphateBFA, Brefeldin ACARTS, CARriers of the TGN to the cell SurfaceCI-MPR, cation-independent mannose-6 phosphate receptorConstitutive SecretionCtBP3/BARS, C-terminus binding protein 3/BFA adenosine diphosphate–ribosylated substrateER, endoplasmic reticulumGlcCer, glucosylceramidetolGolgi to plasma membrane sortingGPI-anchored proteins, glycosylphosphatidylinositol-anchored proteinsPAUF, pancreatic adenocarcinoma up-regulated factorPKD, Protein Kinase Dpleomorphic tubular carrierspost-Golgi carriersRUSH, retention using selective hooksSBP, streptavidin-binding peptideSecretionSM, sphingomyelinSNARE, soluble N-ethylmaleimide sensitive fusion protein attachment protein receptorSPCA1, secretory pathway calcium ATPase 1TGN, trans-Golgi NetworkTIRF, total internal reflection fluorescencets, temperature sensitiveVSV, vesicular stomatitis virus

Identifiers

PMID32317144
PMCPMC7152905
OpenAlexW3015975655

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.