Evidence map›Paper›PMID 32317029›Full record

ReviewRadiation oncology (London, England)2020

Recent advances of PET imaging in clinical radiation oncology.

M Unterrainer, C Eze, H Ilhan, S Marschner, O Roengvoraphoj, N S Schmidt-Hegemann, F Walter, W G Kunz, P Munck Af Rosenschöld, R Jeraj and 5 more

Open access · goldAbstract readReview
In one paragraph

Review in Radiation oncology (London, England), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 57 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
57citing papers in PubMed, 2 pooled it
8.7field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

57 citing papers in PubMed, 2 syntheses or guidelines pooled it, 125 citations in OpenAlex.

  1. Pooled it
  2. DEGRO practical guideline for central nervous system radiation necrosis part 1: classification and a multistep approach for diagnosis.Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al] · 2022
    Guideline
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  18. Copper(I)-free syntheses of [Chemical communications (Cambridge, England) · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 6 institutions in 3 countries.

M UnterrainerDepartment of Nuclear Medicine, University Hospital, LMU Munich, Marchioninistr. 15, 81377, Munich, Germany. marcus.unterrainer@med.uni-muenchen.de.
C EzeDepartment of Radiation Oncology, University Hospital, LMU Munich, Munich, Germany.
H IlhanDepartment of Nuclear Medicine, University Hospital, LMU Munich, Marchioninistr. 15, 81377, Munich, Germany.
S MarschnerDepartment of Radiation Oncology, University Hospital, LMU Munich, Munich, Germany.
O RoengvoraphojDepartment of Radiation Oncology, University Hospital, LMU Munich, Munich, Germany.
N S Schmidt-HegemannDepartment of Radiation Oncology, University Hospital, LMU Munich, Munich, Germany.
F WalterDepartment of Radiation Oncology, University Hospital, LMU Munich, Munich, Germany.
W G KunzDepartment of Radiology, University Hospital, LMU Munich, Marchioninistr. 15, 81377, Munich, Germany.
P Munck Af RosenschöldRadiation Physics, Department of Hematology, Oncology and Radiation Physics, Skåne University Hospital, and Lund University, Lund, Sweden.
R JerajDepartment of Medical Physics, School of Medicine and Public Health, University of Wisconsin-Madison, Madison, USA.
N L AlbertDepartment of Nuclear Medicine, University Hospital, LMU Munich, Marchioninistr. 15, 81377, Munich, Germany.
A L GrosuDepartment of Radiation Oncology, Medical Center - University of Freiburg, Faculty of Medicine, University of Freiburg, Freiburg, Germany.
M NiyaziGerman Cancer Consortium (DKTK), partner site Munich; and German Cancer Research Center (DKFZ), Heidelberg, Germany.
P BartensteinDepartment of Nuclear Medicine, University Hospital, LMU Munich, Marchioninistr. 15, 81377, Munich, Germany.
C BelkaGerman Cancer Consortium (DKTK), partner site Munich; and German Cancer Research Center (DKFZ), Heidelberg, Germany.
Ludwig-Maximilians-Universität München · DELMU Klinikum · DEHeidelberg University · DELund University · SEUniversity of Freiburg · DEUniversity of Wisconsin–Madison · US

Funding

Waiver Option Waiver Option
6 · The paper itself

Abstract

Radiotherapy and radiation oncology play a key role in the clinical management of patients suffering from oncological diseases. In clinical routine, anatomic imaging such as contrast-enhanced CT and MRI are widely available and are usually used to improve the target volume delineation for subsequent radiotherapy. Moreover, these modalities are also used for treatment monitoring after radiotherapy. However, some diagnostic questions cannot be sufficiently addressed by the mere use standard morphological imaging. Therefore, positron emission tomography (PET) imaging gains increasing clinical significance in the management of oncological patients undergoing radiotherapy, as PET allows the visualization and quantification of tumoral features on a molecular level beyond the mere morphological extent shown by conventional imaging, such as tumor metabolism or receptor expression. The tumor metabolism or receptor expression information derived from PET can be used as tool for visualization of tumor extent, for assessing response during and after therapy, for prediction of patterns of failure and for definition of the volume in need of dose-escalation. This review focuses on recent and current advances of PET imaging within the field of clinical radiotherapy / radiation oncology in several oncological entities (neuro-oncology, head & neck cancer, lung cancer, gastrointestinal tumors and prostate cancer) with particular emphasis on radiotherapy planning, response assessment after radiotherapy and prognostication.

Indexed as

Positron-Emission TomographyRadiation OncologyBiomarkers, TumorDisease ProgressionHumansMolecular ImagingNeoplasmsNeoplasm StagingRadiopharmaceuticalsRadiotherapy Planning, Computer-AssistedBiomarkers, TumorRadiopharmaceuticalsGI malignanciesHead & neck cancerLung cancerNeuro-oncologyPETProstate cancerRadiation oncology

Identifiers

PMID32317029
PMCPMC7171749
OpenAlexW3016871628

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.