ArticleJournal of the American Heart Association2020
Chronic Disease Burden After Congenital Heart Surgery: A 47-Year Population-Based Study With 99% Follow-Up.
Article in Journal of the American Heart Association, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.
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Who cites it
25 citing papers in PubMed.
- Health and Well-Being in Older Adults With a Surgically Closed or an Unrepaired Ventricular Septal Defect.Journal of the American Heart Association · 2023Trial
- Integrating optimal patient-centered care: patient- and family-reported experiences after complex treatment for rare diseases.World journal of pediatrics : WJP · 2026Article
- Health Care Utilization in Adults With Congenital Heart Disease: Population-Based Findings.Birth defects research · 2026Article
- Trends and projections in the burden of congenital heart disease among children under 5 years, 1990-2035.Translational pediatrics · 2026Article
- Global burden of developmental intellectual disability in children and adolescents with congenital heart disease, 1990-2021: a population-based study.Translational pediatrics · 2026Article
- Association Between Congenital Heart Disease Complexity, Mental Health Conditions and Opioid Use Disorder.JACC. Advances · 2025Article
- Health Outcomes in Childhood Cancer Survivors with Congenital Anomalies in the Childhood Cancer Survivor Study.Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology · 2025Article
- Framework for Kidney Health Follow-Up Among Neonates With Critical Cardiac Disease: A Report From the Neonatal Kidney Health Consensus Workshop.Journal of the American Heart Association · 2025Review
- Global, regional, and national burden of congenital heart disease, 1990-2021: a systematic analysis for the global burden of disease study 2021.European journal of pediatrics · 2025Article
- Body image of men and women with congenital heart disease over a 15 years observational period.Scientific reports · 2025Article
- Global burden of heart failure in children and adolescents from 1990 to 2019: an analysis from the Global Burden of Disease Study 2019.World journal of pediatrics : WJP · 2025Article
- Pulmonary function impairment and its relationship with target therapy response in patients with pulmonary arterial hypertension.Frontiers in medicine · 2025Article
- Global, regional, and national burdens of heart failure in adolescents and young adults aged 10-24 years from 1990 to 2021: an analysis of data from the Global Burden of Disease Study 2021.EClinicalMedicine · 2025Article
- Morbidity Burden in Patients With Ebstein Anomaly: The Natural History.Journal of the American Heart Association · 2024Article
- Temporal Trend in Hospitalization Among Patients With Congenital Heart Disease: A Danish Nationwide Study.Journal of the American Heart Association · 2024Article
- Psychiatric morbidity and work participation in patients with congenital ventricular septal defects: a case-controlled study.European heart journal. Quality of care & clinical outcomes · 2024Article
- Cardiomyocyte proliferation and regeneration in congenital heart disease.Pediatric discovery · 2024Article
- PICS/AEPC/APPCS/CSANZ/SCAI/SOLACI: Expert Consensus Statement on Cardiac Catheterization for Pediatric Patients and Adults With Congenital Heart Disease.Journal of the Society for Cardiovascular Angiography & Interventions · 2024Article
- Association of Maternal Folate Intake and Offspring MTHFD1 and MTHFD2 Genes with Congenital Heart Disease.Nutrients · 2023Article
- Lifetime Burden of Morbidity in Patients With Isolated Congenital Ventricular Septal Defect.Journal of the American Heart Association · 2023Article
Corrections and comments
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Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background Postoperative morbidity is an increasingly important outcome measure of patients who have undergone congenital heart surgery (CHS). We examined late postoperative morbidity after CHS on the basis of patients' government-issued medical special reimbursement rights. Methods and Results Between 1953 and 2009, 10 635 patients underwent CHS at <15 years of age in Finland. We excluded early deaths and mental disabilities. Noncyanotic and cyanotic defects were divided into simple and severe groups, respectively. We obtained 4 age-, sex-, birth time-, and hospital district-matched control subjects per patient. The Social Insurance Institution of Finland provided data on all medical special reimbursement rights granted between 1966 and 2012. Follow-up started at the first operation and ended at death, date of emigration, or December 31, 2012. A total of 8623 patients met inclusion criteria. Follow-up was 99.9%. A total of 3750 patients (43%) required special reimbursements rights for a chronic disease. Cardiovascular disease was the most common late morbidity among patients (28%), followed by obstructive pulmonary disease (9%), neurologic disease (3%), and psychiatric disease (2%). Heart failure (simple hazard ratio [HR], 56.3 [95% CI, 35.4-89.7]; severe HR, 918.0 [95% CI, 228.9-3681.7]) and arrhythmia (simple HR, 11.0 [95% CI, 7.1-17.0]; severe HR, 248.0 [95% CI, 61.3-1002.7]) were the most common cardiovascular morbidities. Hypertension was common among patients with coarctation of the aorta (13%; incidence risk ratio [RR], 8.9; 95% CI, 7.5-10.7). Psychiatric disease was more common among simple defects, particularly ventricular septal defects. Conclusions Chronic cardiac and noncardiac sequelae are common after CHS regardless of the severity of the defect, underscoring the importance of long-term follow-up of all patients after CHS.
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