Observational studyJournal of the American Heart Association2020
Social Determinants of Health and 90-Day Mortality After Hospitalization for Heart Failure in the REGARDS Study.
Observational study in Journal of the American Heart Association, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 61 papers, 3 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
61 citing papers in PubMed, 3 syntheses or guidelines pooled it.
- Socio-economic inequalities and heart failure morbidity and mortality: A systematic review and data synthesis.ESC heart failure · 2025Pooled it
- Influence of Social Determinants of Health on Heart Failure Outcomes: A Systematic Review.Journal of the American Heart Association · 2023Pooled it
- Fatigue in Persons With Heart Failure: A Systematic Literature Review and Meta-Synthesis Using the Biopsychosocial Model of Health.Journal of cardiac failure · 2022Pooled it
- Neighborhood-Level Socially Determined Vulnerabilities and Outcomes After Heart Failure Hospitalization.Journal of the American Heart Association · 2026Article
- Diuretic Intensity Score and Mortality in Hospitalized Heart Failure Patients: A Multicenter Propensity-Matched Analysis.Clinical cardiology · 2026Article
- Association of social determinants of health and psychological distress among adults in the united states: a cross-sectional study.Social psychiatry and psychiatric epidemiology · 2026Article
- Social determinants of health and hospitalization risk in heart failure: A Retrospective analysis.American heart journal plus : cardiology research and practice · 2026Article
- Racial and Ethnic Inequalities Among Survivors of Critical Illness in the MIMIC-IV Database.Journal of intensive care medicine · 2026Article
- Practical Considerations for using Social Determinants of Health for Disease Prediction in All of Us.Research square · 2026Article
- Thyroid feedback quantile-based index predicts 90-day all-cause mortality or readmission in hospitalized heart failure patients: a retrospective cohort study.Frontiers in endocrinology · 2026Article
- Social Determinants of Health and Patient Experiences During Transitions From Inpatient Rehabilitation to Home.Journal of patient experience · 2026Article
- Practical considerations for social determinant-based disease prediction in the All of Us research program.Communications health · 2026Article
- A prospective analysis of management and outcomes of worsening heart failure in the outpatient setting.ESC heart failure · 2025Observational
- Article
- SBDH-Reader: a large language model-powered method for extracting social and behavioral determinants of health from clinical notes.Journal of the American Medical Informatics Association : JAMIA · 2025Article
- Social Determinants of Health and 30-Day Readmission for Heart Failure Patients in U.S. Hospitals: Evidence from ICD-10 Z-Code Data.Healthcare (Basel, Switzerland) · 2025Article
- Evaluation of the effectiveness of a digital-intelligent-system-based implementation strategy in improving the quality of prehospital medical care: rationale and design of a stepped-wedge cluster randomized controlled trial.BMC health services research · 2025Article
- Patient-Reported Social Determinants of Health in Patients With Heart Failure.Journal of the American Heart Association · 2025Observational
- The application of neighborhood area deprivation index to improve health equity across the spectrum of heart failure: a review.Heart failure reviews · 2025Review
- Association of polysocial risk score, cardiovascular health status, and the risk of premature mortality: Findings from the UK Biobank.The journal of nutrition, health & aging · 2025Article
1 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors.
Funding
Abstract
Background Outcomes following heart failure (HF) hospitalizations are poor, with 90-day mortality rates of 15% to 20%. Although prior studies found associations between individual social determinants of health (SDOH) and post-discharge mortality, less is known about how an individuals' total burden of SDOH affects 90-day mortality. Methods and Results We included participants of the REGARDS (Reasons for Geographic and Racial Differences in Stroke) Study who were Medicare beneficiaries aged ≥65 years discharged alive after an adjudicated HF hospitalization. Guided by the Healthy People 2020 Framework, we examined 9 SDOH. First, we examined age-adjusted associations between each SDOH and 90-day mortality; those associated with 90-day mortality were used to create an SDOH count. Next, we determined the hazard of 90-day mortality by the SDOH count, adjusting for confounders. Over 10 years, 690 participants were hospitalized for HF at 440 unique hospitals in the United States; there were a total of 79 deaths within 90 days. Overall, 28% of participants had 0 SDOH, 39% had 1, and 32% had ≥2. Compared with those with 0, the age-adjusted hazard ratio for 90-day mortality among those with 1 SDOH was 2.89 (95% CI, 1.46-5.72) and was 3.06 (1.51-6.19) among those with ≥2 SDOH. The adjusted hazard ratio was 2.78 (1.37-5.62) and 2.57 (1.19-5.54) for participants with 1 SDOH and ≥2, respectively. Conclusions While having any of the SDOH studied here markedly increased risk of 90-day mortality after an HF hospitalization, a greater burden of SDOH was not associated with significantly greater risk in our population.
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