Evidence map›Paper›PMID 32316571›Full record

ArticleToxins2020

Neuroprotective and Anti-Neuroinflammatory Effects of a Poisonous Plant

Deepak Prasad Gupta, Sung Hee Park, Hyun-Jeong Yang, Kyoungho Suk, Gyun Jee Song

Open access · goldAbstract read
In one paragraph

Article in Toxins, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
1.4field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 16 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Article
  6. Article
  7. Article
  8. Review
  9. Article
  10. Article
  11. Article
  12. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 4 institutions in 1 country.

Deepak Prasad GuptaDepartment of Medical Science, College of Medicine, Catholic Kwandong University, Gangneung, Gangwon-do 25601, Korea.
Sung Hee ParkDepartment of Medical Science, College of Medicine, Catholic Kwandong University, Gangneung, Gangwon-do 25601, Korea.
Hyun-Jeong YangDepartment of Integrative Biosciences, University of Brain Education, Cheonan 31228, Korea.
Kyoungho SukDepartment of Pharmacology, Brain Science and Engineering Institute, BK21 Plus KNU Biomedical Convergence Program, School of Medicine, Kyungpook National University, Daegu 41944, Korea.
Gyun Jee SongDepartment of Medical Science, College of Medicine, Catholic Kwandong University, Gangneung, Gangwon-do 25601, Korea.
Kyungpook National University · KRCatholic Kwandong University · KRCatholic Kwandong University International St. Mary's Hospital · KRUniversity of Brain Education · KR

Funding

Brain Science Research Program NRF-2015M3C7A1028392National Research Foundation NRF 2016R1D 1A 1B 01009186
6 · The paper itself

Abstract

Neuroinflammation is involved in various neurological diseases. Activated microglia secrete many pro-inflammatory factors and induce neuronal cell death. Thus, the inhibition of excessive proinflammatory activity of microglia leads to a therapeutic effect that alleviates the progression of neuronal degeneration. In this study, we investigated the effect of

Indexed as

CrotonPlants, ToxicAnimalsAnti-Inflammatory AgentsAstrocytesCell LineCell SurvivalLipopolysaccharidesMiceMicrogliaNeuronsNeuroprotective AgentsNitric OxidePhagocytosisPlant ExtractsRatsAnti-Inflammatory AgentsLipopolysaccharidesNeuroprotective AgentsNitric OxidePlant ExtractsTumor Necrosis Factor-alphaCroton tiglium Linn., neuroprotectionM2 phenotypemicroglianeuroinflammationpoisonous plant

Identifiers

PMID32316571
PMCPMC7232518
OpenAlexW3016493105

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.