Evidence map›Paper›PMID 32316518›Full record

ArticleAntibiotics (Basel, Switzerland)2020

Effects of Antibiotics on the Intestinal Microbiota of Mice.

Frederik Boetius Hertz, Andries E Budding, Malieka van der Lugt-Degen, Paul H Savelkoul, Anders Løbner-Olesen, Niels Frimodt-Møller

Open access · goldAbstract read
In one paragraph

Article in Antibiotics (Basel, Switzerland), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed
2.0field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 36 citations in OpenAlex.

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  11. Antibiotic perturbations to the gut microbiome.Nature reviews. Microbiology · 2023
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 4 institutions in 2 countries.

Frederik Boetius HertzDepartment of Clinical Microbiology, Hvidovre University Hospital, 2650 Copenhagen, Denmark.
Andries E BuddingDepartment of Medical Microbiology & Infection Control, University Medical Centers, Location VUmc, 1081 HV Amsterdam, The Netherlands.
Malieka van der Lugt-DegenDepartment of Medical Microbiology & Infection Control, University Medical Centers, Location VUmc, 1081 HV Amsterdam, The Netherlands.
Paul H SavelkoulDepartment of Medical Microbiology & Infection Control, University Medical Centers, Location VUmc, 1081 HV Amsterdam, The Netherlands.
Anders Løbner-OlesenDepartment of Biology, University of Copenhagen, 2200 Copenhagen, Denmark.ORCID 0000-0002-0344-6417
Niels Frimodt-MøllerDepartment of Clinical Microbiology, Rigshospitalet, 2100 Copenhagen, Denmark.
Hvidovre Hospital · DKMaastricht University · NLRigshospitalet · DKUniversity of Copenhagen · DK

Funding

Aase og Ejnar Danielsens Fond 0FP7 Health EU-FP7-Health-2009-Single-Stage projectScandinavian Society for Antimicrobial Chemotherapy Foundation SLS-251761Scandinavian Society for Antimicrobial Chemotherapy Foundation SLS-327421Strategiske Forskningsråd 09-067075/DSF
6 · The paper itself

Abstract

Studies on human and mouse gastrointestinal microbiota have correlated the composition of the microbiota to a variety of diseases, as well as proved it vital to prevent colonization with resistant bacteria, a phenomenon known as colonization resistance. Antibiotics dramatically modify the gut community and there are examples of how antibiotic usage lead to colonization with resistant bacteria [e.g., dicloxacillin usage selecting for ESBL-producing

Indexed as

16Santibioticsdicloxacillinintestinal microbiotaIS-pro

Identifiers

PMID32316518
PMCPMC7235770
OpenAlexW3017087313

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.