Evidence map›Paper›PMID 32316452›Full record

ArticleInternational journal of molecular sciences2020

Similar Yet Different-Structural and Functional Diversity among

Patrick Knox-Brown, Tobias Rindfleisch, Anne Günther, Kim Balow, Anne Bremer, Dirk Walther, Markus S Miettinen, Dirk K Hincha, Anja Thalhammer

Open access · goldAbstract readComparative Study
In one paragraph

Article in International journal of molecular sciences, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
1.0field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 29 citations in OpenAlex.

  1. Article
  2. Biomolecular condensates-Prerequisites for anhydrobiosis?Protein science : a publication of the Protein Society · 2025
    Review
  3. Article
  4. Review
  5. Article
  6. Article
  7. Plants (Basel, Switzerland) · 2023
    Article
  8. Review
  9. Article
  10. Article
  11. Article
  12. Article
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  15. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 2 countries.

Patrick Knox-BrownPhysical Biochemistry, University of Potsdam, Karl-Liebknecht-Str. 24-25, D-14476 Potsdam, Germany.
Tobias RindfleischPhysical Biochemistry, University of Potsdam, Karl-Liebknecht-Str. 24-25, D-14476 Potsdam, Germany.ORCID 0000-0003-0329-0544
Anne GüntherMax-Planck Institute of Molecular Plant Physiology, Am Mühlenberg 1, D-14476 Potsdam, Germany.
Kim BalowMax-Planck Institute of Molecular Plant Physiology, Am Mühlenberg 1, D-14476 Potsdam, Germany.
Anne BremerMax-Planck Institute of Molecular Plant Physiology, Am Mühlenberg 1, D-14476 Potsdam, Germany.
Dirk WaltherMax-Planck Institute of Molecular Plant Physiology, Am Mühlenberg 1, D-14476 Potsdam, Germany.ORCID 0000-0002-5755-9265
Markus S MiettinenMax-Planck Institute of Colloids and Interfaces, Am Mühlenberg 1, D-14476 Potsdam, Germany.ORCID 0000-0002-3999-4722
Dirk K HinchaMax-Planck Institute of Molecular Plant Physiology, Am Mühlenberg 1, D-14476 Potsdam, Germany.ORCID 0000-0001-6887-4933
Anja ThalhammerPhysical Biochemistry, University of Potsdam, Karl-Liebknecht-Str. 24-25, D-14476 Potsdam, Germany.ORCID 0000-0002-6480-0993
Max Planck Institute of Molecular Plant Physiology · DEUniversity of Potsdam · DEMax Planck Institute of Colloids and Interfaces · DESt. Jude Children's Research Hospital · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The importance of intrinsically disordered late embryogenesis abundant (LEA) proteins in the tolerance to abiotic stresses involving cellular dehydration is undisputed. While structural transitions of LEA proteins in response to changes in water availability are commonly observed and several molecular functions have been suggested, a systematic, comprehensive and comparative study of possible underlying sequence-structure-function relationships is still lacking. We performed molecular dynamics (MD) simulations as well as spectroscopic and light scattering experiments to characterize six members of two distinct, lowly homologous clades of LEA_4 family proteins from

Indexed as

ArabidopsisArabidopsis ProteinsComputational BiologyModels, MolecularMolecular ConformationMolecular Dynamics SimulationProtein FoldingStress, PhysiologicalArabidopsis Proteinsabiotic stressconformational rearrangementdehydrationIDPLEA proteinmembrane stabilizationsequence-structure-function relationship

Identifiers

PMID32316452
PMCPMC7215670
OpenAlexW3016334086

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.