ArticleSensors (Basel, Switzerland)2020
Ultrasound Standing Wave-Based Cell-to-liquid Separation for Measuring Viscosity and Aggregation of Blood Sample.
Article in Sensors (Basel, Switzerland), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
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Who cites it
11 citing papers in PubMed.
- Continuous Measurement of Spatially Resolved Red Blood Cell Aggregation Using Multiple Side-Branch Channels.Biosensors · 2026Article
- A Pulsatile Flow-Modulation Microfluidic Sensor for Simultaneous Monitoring of Red Blood Cell Aggregation and Viscosity-Sensitive Time Constant.Sensors (Basel, Switzerland) · 2026Article
- A Microfluidic Method for Simultaneous Assessment of Blood Viscosity and Red Blood Cell Aggregation During Continuous Syringe Delivery.Sensors (Basel, Switzerland) · 2026Article
- Full Hematocrit-Viscosity Curve Identification Using Three-Dataset Krieger-Dougherty Regression.Biosensors · 2026Article
- Micro Blood Flow-Resolved Rheometry.Micromachines · 2026Article
- Biomechanical Investigation of Red Cell Sedimentation Using Blood Shear Stress and Blood Flow Image in a Capillary Chip.Micromachines · 2023Article
- Biomechanical Assessment of Red Blood Cells in Pulsatile Blood Flows.Micromachines · 2023Article
- Strain Sensor-Inserted Microchannel for Gas Viscosity Measurement.Biosensors · 2023Article
- Red Blood Cell Sedimentation Index Using Shear Stress of Blood Flow in Microfluidic Channel.Biosensors · 2022Article
- Contributions of Red Blood Cell Sedimentation in a Driving Syringe to Blood Flow in Capillary Channels.Micromachines · 2022Article
- Comparing of Frequency Shift and Impedance Analysis Method Based on QCM Sensor for Measuring the Blood Viscosity.Sensors (Basel, Switzerland) · 2022Article
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Authors and funding
3 authors.
Funding
Abstract
When quantifying mechanical properties of blood samples flowing in closed fluidic circuits, blood samples are collected at specific intervals. Centrifugal separation is considered as a required procedure for preparing blood samples. However, the use of centrifuge is associated with several issues, including the potential for red blood cell (RBC) lysis, clotting activation, and RBC adhesions in the tube. In this study, an ultrasonic transducer is employed to separate RBCs or diluent from blood sample. The ultrasonic radiation force is much smaller than the centrifugal force acting in centrifuge, it can avoid critical issues occurring under centrifuge. Then, the RBC aggregation and blood viscosity of the blood sample are obtained using the microfluidic technique. According to the numerical results, ultrasonic transducers exhibited a maximum quality factor at an excitation frequency of 2.1 MHz. Periodic pattern of acoustic pressure fields were visualized experimentally as a column mode. The half wavelength obtained was as 0.5 λ = 0.378 ± 0.07 mm. The experimental results agreed with the analytical estimation sufficiently. An acoustic power of 2 W was selected carefully for separating RBCs or diluent from various blood samples (i.e.,
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