Evidence map›Paper›PMID 32316314›Full record

ArticleNutrients2020

A Study on the Relationship between Type 2 Diabetes and Taste Function in Patients with Good Glycemic Control.

Sofia Pugnaloni, Sonila Alia, Margherita Mancini, Vito Santoro, Alice Di Paolo, Rosa Anna Rabini, Rosamaria Fiorini, Jacopo Sabbatinelli, Mara Fabri, Laura Mazzanti and 1 more

Open access · goldAbstract read
In one paragraph

Article in Nutrients, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.

0numbers the graph read from it
0cells of the map it votes in
26citing papers in PubMed
2.9field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

26 citing papers in PubMed, 45 citations in OpenAlex.

  1. Article
  2. Observational
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  7. Organoid models for chemosensing cell studies.American journal of physiology. Cell physiology · 2025
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  14. Article
  15. Observational
  16. Review
  17. Frontiers in pharmacology · 2022
    Article
  18. Article
  19. Article
  20. Hepatic-Metabolite-Based Intermittent Fasting Enables a Sustained Reduction in Insulin Resistance in Type 2 Diabetes and Metabolic Syndrome.Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 2 institutions in 1 country.

Sofia PugnaloniDepartment of Clinical Sciences, Section of Biochemistry, Biology and Physics, Università Politecnica delle Marche, Via Tronto 10/A, 60126 Ancona, Italy.ORCID 0000-0003-1499-8943
Sonila AliaDepartment of Clinical Sciences, Section of Biochemistry, Biology and Physics, Università Politecnica delle Marche, Via Tronto 10/A, 60126 Ancona, Italy.
Margherita ManciniDepartment of Clinical Sciences, School of Specialization in Clinical Nutrition, Università Politecnica delle Marche, Via Tronto 10/A, 60126 Ancona, Italy.
Vito SantoroDepartment of Clinical Sciences, School of Specialization in Clinical Nutrition, Università Politecnica delle Marche, Via Tronto 10/A, 60126 Ancona, Italy.
Alice Di PaoloDepartment of Clinical Sciences, Section of Biochemistry, Biology and Physics, Università Politecnica delle Marche, Via Tronto 10/A, 60126 Ancona, Italy.
Rosa Anna RabiniDiabetology Department, IRCCS INRCA, Via della Montagnola 81, 60127 Ancona, Italy.
Rosamaria FioriniDepartment of Life and Environmental Sciences, Università Politecnica delle Marche, Via Brecce Bianche, 60131 Ancona, Italy.
Jacopo SabbatinelliDepartment of Clinical Sciences, Section of Biochemistry, Biology and Physics, Università Politecnica delle Marche, Via Tronto 10/A, 60126 Ancona, Italy.ORCID 0000-0001-9947-6778
Mara FabriDepartment of Experimental and Clinical Medicine, Università Politecnica delle Marche, Via Tronto 10/A, 60126 Ancona, Italy.
Laura MazzantiDepartment of Clinical Sciences, Section of Biochemistry, Biology and Physics, Università Politecnica delle Marche, Via Tronto 10/A, 60126 Ancona, Italy.
Arianna VigniniDepartment of Clinical Sciences, Section of Biochemistry, Biology and Physics, Università Politecnica delle Marche, Via Tronto 10/A, 60126 Ancona, Italy.
Marche Polytechnic University · ITIstituti di Ricovero e Cura a Carattere Scientifico · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Type 2 diabetes mellitus (T2DM) has a very high impact on quality of life as it is characterized by disabling complications. There is little evidence about taste alterations in diabetes. Since many individual factors are involved in the onset of diabetes, the purpose of our study is to search a possible link between diabetes and individual taste function. Thirty-two participants with T2DM and 32 volunteers without T2DM (healthy controls) were recruited. Four concentrations of each of the four basic tastes (sweet, sour, salty, bitter), and pure rapeseed oil and water, were applied with cotton pads to the protruded tongue, immediately posterior to its first third, either to the left or right side. The results showed significant differences between groups in the ability to recognize sour, bitter, sweet, and water. Taste scores were lower in subjects with T2DM than in healthy controls, and an age-related decline in taste function was found. The taste function reduction associated with T2DM was not related to gender, disease duration, and glycemic control. In conclusion, it can be hypothesized that a general alteration of taste function can lead patients with type 2 diabetes to search for foods richer in sugars, as in a vicious circle, thus decreasing the likelihood of remission of diabetes mellitus.

Indexed as

TasteAdolescentAdultAgedAgingDiabetes Mellitus, Type 2Diet, DiabeticFemaleGlycated HemoglobinHumansHypoglycemic AgentsMaleMiddle AgedYoung AdultGlycated Hemoglobinhemoglobin A1c protein, humanHypoglycemic Agentsdiabetesfood preferencesgendertaste function

Identifiers

PMID32316314
PMCPMC7230282
OpenAlexW3016442855

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.