ArticleiScience2020
Variable Assembly of EMRE and MCU Creates Functional Channels with Distinct Gatekeeping Profiles.
Article in iScience, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
19 citing papers in PubMed, 29 citations in OpenAlex.
- Reconstructing calcium conductance in MCUb illuminates its molecular design for tuning the mitochondrial calcium uniporter.Nature communications · 2026Article
- Mechano-energetic uncoupling in heart failure.Nature reviews. Cardiology · 2025Review
- Mitochondrial CaJournal of cellular physiology · 2025Review
- Mechanism of MCUB-Dependent Inhibition of Mitochondrial Calcium Uptake.Journal of cellular physiology · 2025Article
- The Mitochondrial Calcium Uniporter (MCU): Molecular Identity and Role in Human Diseases.Biomolecules · 2023Review
- MICU1 occludes the mitochondrial calcium uniporter in divalent-free conditions.Proceedings of the National Academy of Sciences of the United States of America · 2023Article
- Mitochondrial calcium exchange in physiology and disease.Physiological reviews · 2022Review
- Quantitative analysis of mitochondrial calcium uniporter (MCU) and essential MCU regulator (EMRE) in mitochondria from mouse tissues and HeLa cells.FEBS open bio · 2022Article
- Structural characterization of the mitochondrial CaiScience · 2021Review
- MitopatHs: a new logically-framed tool for visualizing multiple mitochondrial pathways.iScience · 2021Article
- Molecular nature and physiological role of the mitochondrial calcium uniporter channel.American journal of physiology. Cell physiology · 2021Review
- Uncorking MCU to let the calcium flow.Cell calcium · 2020Article
- The structure of the MICU1-MICU2 complex unveils the regulation of the mitochondrial calcium uniporter.The EMBO journal · 2020Article
- Regulation of CaCurrent opinion in physiology · 2020Article
- Structure and Reconstitution of an MCU-EMRE Mitochondrial CaJournal of molecular biology · 2020Article
- Coupled transmembrane mechanisms control MCU-mediated mitochondrial CaProceedings of the National Academy of Sciences of the United States of America · 2020Article
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- Oxygen Glucose Deprivation Induced Prosurvival Autophagy Is Insufficient to Rescue Endothelial Function.Frontiers in physiology · 2020Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 1 institution in 1 country.
Funding
Abstract
MCU is a Ca
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.