ArticleEnvironmental research2020
Greater tree cover near residence is associated with reduced allostatic load in residents of central North Carolina.
Article in Environmental research, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 3 of them syntheses that pooled it.
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Who cites it
21 citing papers in PubMed, 3 syntheses or guidelines pooled it.
- Does the biodiversity of urban green spaces impact on human health? A systematic review of literature.BMC public health · 2026Pooled it
- Allostatic Load Measurement: A Systematic Review of Reviews, Database Inventory, and Considerations for Neighborhood Research.International journal of environmental research and public health · 2022Pooled it
- Green Space Quality and Health: A Systematic Review.International journal of environmental research and public health · 2021Pooled it
- Precision residential greenspace, urban environmental exposures, and incident dementia among older adults in Sweden: A 16-year cohort study.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2026Article
- Associations between volatile organic compound mixtures and allostatic load: Evidence from the Green Heart Louisville Project.Environmental research · 2026Article
- Residential tree canopy and allostatic load in US adults: a population-based cross-sectional study.Lancet regional health. Americas · 2026Article
- Stress, Well-Being, and Reproduction in Wildlife.Advances in experimental medicine and biology · 2026Review
- Beyond microbial exposure and colonization: multisensory shaping of the gut microbiome.mSystems · 2025Review
- Disparities in Allostatic Load Among Different Races: A Comprehensive Scoping Review.Journal of racial and ethnic health disparities · 2025Review
- Associations between neighborhood greenery and birth outcomes in a North Carolina cohort.Journal of exposure science & environmental epidemiology · 2025Article
- Association between neighborhood stressors and allostatic load in breast cancer survivors: the Pathways Study.American journal of epidemiology · 2025Article
- Urology on a changing planet: links between climate change and urological disease.Nature reviews. Urology · 2025Review
- Pilot application of an inflammation and physiological dysregulation index based on noninvasive salivary biomarkers.BMC research notes · 2025Article
- Greater residential greenness is associated with reduced epigenetic aging in adults.Scientific reports · 2025Article
- Association between exposure to greenspace and ECG abnormalities in China: a nationwide longitudinal study.BMC public health · 2024Article
- Potential causal links and mediation pathway between urban greenness and lung cancer mortality: Result from a large cohort (2009 to 2020).Sustainable cities and society · 2024Article
- Fine particulate matter-sudden death association modified by ventricular hypertrophy and inflammation: a case-crossover study.Frontiers in public health · 2024Article
- Influence of Neighborhood Social and Natural Environment on Prostate Tumor Histology in a Cohort of Male Health Professionals.American journal of epidemiology · 2023Article
- Architectural Allostatic Overloading: Exploring a Connection between Architectural Form and Allostatic Overloading.International journal of environmental research and public health · 2023Article
- Critical windows of exposure to air pollution and gestational diabetes: assessing effect modification by maternal pre-existing conditions and environmental factors.Environmental health : a global access science source · 2023Article
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Authors and funding
9 authors.
Funding
Abstract
backgroundAmong urban residents, increased contacts with nature are associated with reduced morbidity and mortality. The concept of allostatic load, a biomarker-based composite measure of physiological dysregulation, can be applied to study subclinical benefits of exposure, and to elucidate pathways leading to improved health.
objectiveThis research explored associations between residential vegetated land cover and an allostatic load index calculated using the statistical distance measure known as Mahalanobis distance.
methodsThis cross-sectional population-based study involved 186 adult residents of the Durham-Chapel Hill, North Carolina metropolitan area. Measures of tree and grass cover within 500 m of residence were derived from the U.S. Environmental Protection Agency's EnviroAtlas land cover database. Fifteen biomarkers of immune, neuroendocrine, and metabolic functions were analyzed in serum samples. Regression analysis was conducted using generalized additive models with thin-plate spline functions of geographic coordinates, adjusting for modelled traffic air pollution from local sources and sociodemographic covariates.
resultsThe second and third tertiles of distance-weighted tree cover were associated with 14% (95% Confidence Limits 20%; 8%) and 15% (21%; 8%) reduction in adjusted median allostatic load, respectively, compared to the first tertile. The same tertiles of tree cover were also associated with 0.16 (0.03; 0.76) and 0.04 (0.01; 0.35) adjusted odds ratios of having allostatic load index above the 90th percentile of the sample distribution. Grass cover was inversely correlated with tree cover and was not associated with reduced allostatic load.
conclusionsSubclinical beneficial health effects of green spaces demonstrated in this study are consistent with reduced susceptibility to acute environmental and social stressors, and reduced risks of morbidity and mortality.
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