Evidence map›Paper›PMID 32315649›Full record

ArticleArchives of physical medicine and rehabilitation2020

Establishing the Factor Structure of a Health-Related Quality of Life Measurement System for Caregivers of Persons Living With Traumatic Brain Injury.

Jason H Raad, David S Tulsky, Rael T Lange, Tracey A Brickell, Angelle M Sander, Robin A Hanks, Louis French, Jennifer A Miner, Pamela A Kisala, Noelle E Carlozzi

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Archives of physical medicine and rehabilitation, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.6field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 6 citations in OpenAlex.

  1. Caregiver strain is strongly associated with health and family outcomes in military couples following traumatic brain injury in service members and veterans.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 7 institutions in 2 countries.

Jason H RaadDepartment of Physical Medicine and Rehabilitation, University of Michigan, Ann Arbor, MI.
David S TulskyCenter for Assessment Research and Translation, Department of Psychological and Brain Sciences, University of Delaware, Newark, DE.
Rael T LangeDefense and Veterans Brain Injury Center, Walter Reed National Military Medical Center, Bethesda, MD; National Intrepid Center of Excellence, Walter Reed National Military Medical Center, Bethesda, MD; Defense and Veterans Brain Injury Center, Silver Spring, MD; Faculty of Medicine, University of British Columbia, Vancouver, British Columbia, Canada.
Tracey A BrickellDefense and Veterans Brain Injury Center, Walter Reed National Military Medical Center, Bethesda, MD; National Intrepid Center of Excellence, Walter Reed National Military Medical Center, Bethesda, MD; Defense and Veterans Brain Injury Center, Silver Spring, MD; Edward Hebert School of Medicine, Uniformed Services University of the Health Sciences, Bethesda, MD.
Angelle M SanderH. Ben Taub Department of Physical Medicine and Rehabilitation, Baylor College of Medicine & Harris Health System, Houston, TX; Brain Injury Research Center, TIRR Memorial Hermann, Houston, TX.
Robin A HanksRehabilitation Institute of Michigan, Department of Psychology and Neuropsychology, Detroit, MI; Department of Physical Medicine and Rehabilitation, Wayne State University, Detroit, MI.
Louis FrenchDefense and Veterans Brain Injury Center, Walter Reed National Military Medical Center, Bethesda, MD; National Intrepid Center of Excellence, Walter Reed National Military Medical Center, Bethesda, MD; Edward Hebert School of Medicine, Uniformed Services University of the Health Sciences, Bethesda, MD.
Jennifer A MinerDepartment of Physical Medicine and Rehabilitation, University of Michigan, Ann Arbor, MI.
Pamela A KisalaCenter for Assessment Research and Translation, Department of Psychological and Brain Sciences, University of Delaware, Newark, DE.
Noelle E CarlozziDepartment of Physical Medicine and Rehabilitation, University of Michigan, Ann Arbor, MI. Electronic address: carlozzi@med.umich.edu.
University of Michigan · USDefense & Veterans Center for Integrative Pain Management · USCenter for Assessment · USHarris Health System · USUniversity of Delaware · USWalter Reed National Military Medical Center · USWayne State University · US

Funding

Michigan Institute for Clinical and Health Research (MICHR)UL1TR002240 · NCATS · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI LUMENG, JULIE C, MASHOUR, GEORGE ALEXANDER · 2017 to 2022
$54.9M
Michigan Institute for Clinical and Health Research (MCHR)UL1TR000433 · NCATS · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI MASHOUR, GEORGE ALEXANDER · 2012 to 2016
$49.9M
Quality of Life in Caregivers of Traumatic Brain Injury: The TBI-CareQOLR01NR013658 · NINR · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI CARLOZZI, NOELLE E. · 2012 to 2024
$6.0M
NCATS NIH HHS UL1 TR000433NCATS NIH HHS UL1 TR002240NINR NIH HHS R01 NR013658
6 · The paper itself

Abstract

objectivesTo understand the factor structure of health-related quality of life specific to caregivers of people living with traumatic brain injury (TBI).

designProspective, cross-sectional data collection.

settingThree TBI Model Systems rehabilitation hospitals, an academic medical center, and a military medical treatment facility.

participantsCaregivers (N=558) of people who have sustained a TBI (344 caregivers of civilians and 214 caregivers of service members or veterans; 85% women; 58% spouses; mean age, 46.12±14.07y) who have provided care for an average of 5.82±5.40 years.

interventionsNot applicable. MAIN OUTCOMES MEASURES: The Traumatic Brain Injury Caregiver Quality of Life (TBI-CareQOL) measurement system including 10 Patient-Reported Outcomes Measurement Information System item banks (anger, anxiety, depression, social isolation, sleep disturbance, fatigue, ability to participate in social roles and activities, satisfaction with social roles and activities, emotional support, informational support) and 5 TBI-CareQOL banks (feelings of loss-self, feelings of loss-person with TBI, feeling trapped, caregiver-specific anxiety, caregiver strain).

resultsConfirmatory factor analysis model fit indices were compared for 14 empirically derived and 5 theoretically derived models. Confirmatory factor analysis results indicated that the best model fit was for a 6-factor model with dimensions that included mental health, social support, social participation, social isolation, physical health, and caregiver emotion.

conclusionsResults indicated that a 6-factor model provided the best model fit for health-related quality of life in caregivers of individuals with TBI. These results have utility for both research and clinical applications. Establishing the TBI-CareQOL's factor structure provides preliminary evidence of the measurement system's construct validity, helps inform the selection of measures for specific research or clinical interventions, and informs the development of composite scores.

Indexed as

Quality of LifeAdultAgedAge FactorsBrain Injuries, TraumaticCaregiversCross-Sectional StudiesFemaleHumansInjury Severity ScoreLong-Term CareMaleMiddle AgedPrognosisProspective StudiesPsychometricsBrain injuriesCaregiversPatient reported outcome measuresQuality of lifeRehabilitationVeterans

Identifiers

PMID32315649
PMCPMC7311311
OpenAlexW3017028560

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.