Evidence map›Paper›PMID 32315549›Full record

ArticleCancer biotherapy & radiopharmaceuticals2020

Caleb Bridgwater, Anne Geller, Xiaoling Hu, Joe A Burlison, Huang-Ge Zhang, Jun Yan, Haixun Guo

Open access · greenAbstract read
In one paragraph

Article in Cancer biotherapy & radiopharmaceuticals, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
1.8field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 26 citations in OpenAlex.

  1. Review
  2. Review
  3. PET Imaging of Peptide Probe Al[Molecular pharmaceutics · 2024
    Article
  4. Noninvasive PET imaging of tumor PD-L1 expression withAmerican journal of nuclear medicine and molecular imaging · 2024
    Article
  5. Review
  6. [Cancers · 2023
    Article
  7. Article
  8. Review
  9. Review
  10. Preclinical antibody-PET imaging of PD-L1.Frontiers in nuclear medicine · 2022
    Review
  11. Review
  12. Potentials of Non-InvasiveFrontiers in genetics · 2021
    Review
  13. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Caleb BridgwaterDepartment of Radiology, University of Louisville, Louisville, Kentucky, USA.
Anne GellerDepartment of Microbiology and Immunology, University of Louisville, Louisville, Kentucky, USA.
Xiaoling HuJames Graham Brown Cancer Center, University of Louisville, Louisville, Kentucky, USA.
Joe A BurlisonJames Graham Brown Cancer Center, University of Louisville, Louisville, Kentucky, USA.
Huang-Ge ZhangDepartment of Microbiology and Immunology, University of Louisville, Louisville, Kentucky, USA.
Jun YanDepartment of Microbiology and Immunology, University of Louisville, Louisville, Kentucky, USA.
Haixun GuoDepartment of Radiology, University of Louisville, Louisville, Kentucky, USA.
University of Louisville · US

Funding

University of Louisville Cancer Education ProgramR25CA134283 · NCI · UNIVERSITY OF LOUISVILLE · PI HEIN, DAVID W, KIDD, LA CREIS RENEE · 2011 to 2022
$3.1M
NCI NIH HHS R25 CA134283
6 · The paper itself

Abstract

The rise of programmed death-1 (PD-1)/PD-L1 immune checkpoint inhibitor therapy has been one of the most promising developments in melanoma research. However, not all the melanoma patients respond to such immune checkpoint blockade. There is a great need of biomarkers for appropriate melanoma patient selection and therapeutic efficacy monitoring. The objective of this study is to develop a novel radiolabeled anti-PD-L1 antibody fragment, as an imaging biomarker, for evaluating the

Indexed as

AnimalsB7-H1 AntigenCell Line, TumorDisease Models, AnimalFemaleHumansImmunoconjugatesMelanoma, ExperimentalMiceMolecular ImagingPositron Emission Tomography Computed TomographyRadioisotopesRadiopharmaceuticalsSkin NeoplasmsTissue DistributionZirconiumB7-H1 AntigenCd274 protein, mouseImmunoconjugatesRadioisotopesRadiopharmaceuticalsZirconiumZirconium-89antibody fragmentimmune checkpoint inhibitor therapymelanomaPD-L1 biomarkerPET imaging

Identifiers

PMID32315549
PMCPMC7578182
OpenAlexW3016879630

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.