Evidence map›Paper›PMID 32315335›Full record

ArticlePloS one2020

Spatial distribution of Mycobacterium Tuberculosis in metropolitan Harare, Zimbabwe.

Joconiah Chirenda, Isaiah Gwitira, Robin M Warren, Samantha L Sampson, Amon Murwira, Collen Masimirembwa, Kudzanai M Mateveke, Cremence Duri, Prosper Chonzi, Simbarashe Rusakaniko and 1 more

Open access · goldAbstract read
In one paragraph

Article in PloS one, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed, 1 pooled it
0.6field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 1 synthesis or guideline pooled it, 28 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 2 institutions in 2 countries.

Joconiah ChirendaDepartment of Community Medicine, College of Health Sciences, University of Zimbabwe, Harare, Zimbabwe.ORCID 0000-0003-2441-3304
Isaiah GwitiraDepartment of Geography and Environmental Science, University of Zimbabwe, Harare, Zimbabwe.
Robin M WarrenDivision of Molecular Biology and Human Genetics, NRF/DST Centre of Excellence for Biomedical Tuberculosis Research, South African Medical Research Council Centre for Tuberculosis Research, Faculty of Medicine and Health Sciences, Stellenbosch University, Cape Town, South Africa.
Samantha L SampsonDivision of Molecular Biology and Human Genetics, NRF/DST Centre of Excellence for Biomedical Tuberculosis Research, South African Medical Research Council Centre for Tuberculosis Research, Faculty of Medicine and Health Sciences, Stellenbosch University, Cape Town, South Africa.
Amon MurwiraDepartment of Geography and Environmental Science, University of Zimbabwe, Harare, Zimbabwe.
Collen MasimirembwaDepartment of Community Medicine, College of Health Sciences, University of Zimbabwe, Harare, Zimbabwe.
Kudzanai M MatevekeDepartment of Community Medicine, College of Health Sciences, University of Zimbabwe, Harare, Zimbabwe.
Cremence DuriDepartment of Health, Harare City Council, Harare, Zimbabwe.
Prosper ChonziDepartment of Health, Harare City Council, Harare, Zimbabwe.
Simbarashe RusakanikoDepartment of Community Medicine, College of Health Sciences, University of Zimbabwe, Harare, Zimbabwe.
Elizabeth M StreicherDivision of Molecular Biology and Human Genetics, NRF/DST Centre of Excellence for Biomedical Tuberculosis Research, South African Medical Research Council Centre for Tuberculosis Research, Faculty of Medicine and Health Sciences, Stellenbosch University, Cape Town, South Africa.
University of Zimbabwe · ZWSouth African Medical Research Council · ZA

Funding

Wellcome TrustWellcome Trust WT087537MA
6 · The paper itself

Abstract

introductionThe contribution of high tuberculosis (TB) transmission pockets in propagating area-wide transmission has not been adequately described in Zimbabwe. This study aimed to describe the presence of hotspot transmission of TB cases in Harare city from 2011 to 2012 using geospatial techniques.

methodsAnonymised TB patient data stored in an electronic database at Harare City Health department was analysed using geospatial methods. Confirmed TB cases were mapped using geographic information system (GIS). Global Moran's I and Anselin Local Moran's I (LISA) were used to assess clustering and the local Getis-Ord Gi* was used to estimate hotspot phenomenon of TB cases in Harare City for the period between 2011 and 2012.

resultsA total of 12,702 TB cases were accessed and mapped on the Harare City map. In both 2011 and 2012, ninety (90%) of cases were new and had a high human immunodeficiency virus (HIV)/TB co-infection rate of 72% across all suburbs. Tuberculosis prevalence was highest in the Southern district in both 2011 and 2012. There were pockets of spatial distribution of TB prevalence across West South West, Southern, Western, South Western and Eastern health districts. TB hot spot occurrence was restricted to the West South West, parts of South Western, Western health districts. West South West district had an increased peri-urban population with inadequate social services including health facilities. These conditions were conducive for increased intensity of TB occurrence, a probable indication of high transmission especially in the presence of high HIV co-infection. CONCLUSIONS AND RECOMMENDATIONS: Increased TB transmission was limited to a health district with high informal internal migrants with limited health services in Harare City. To minimise spread of TB into greater Harare, there is need to improve access to TB services in the peri-urban areas.

Indexed as

Disease Transmission, InfectiousAdolescentAdultChildChild, PreschoolFemaleGeographic Information SystemsHealth Services AccessibilityHIVHIV InfectionsHumansMaleMiddle AgedMycobacterium tuberculosisSpatial AnalysisTuberculosis

Identifiers

PMID32315335
PMCPMC7173793
OpenAlexW3016287857

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.