Evidence map›Paper›PMID 32315122›Full record

ArticleAmerican journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons2020

COVID-19 in a high-risk dual heart and kidney transplant recipient.

Jeffrey J Hsu, Pryce Gaynor, Megan Kamath, Ashley Fan, Farah Al-Saffar, Daniel Cruz, Ali Nsair

Open access · hybridAbstract readCase Reports
In one paragraph

Article in American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 34 papers, 8 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
34citing papers in PubMed, 8 pooled it
1.2field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

34 citing papers in PubMed, 8 syntheses or guidelines pooled it, 49 citations in OpenAlex.

  1. Pooled it
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  3. Effect of immunosuppression maintenance in solid organ transplant recipients with COVID-19: Systematic review and meta-analysis.Transplant infectious disease : an official journal of the Transplantation Society · 2021
    Pooled it
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  7. COVID-19 clinical manifestations and treatment strategies among solid-organ recipients: A systematic review of cases.Transplant infectious disease : an official journal of the Transplantation Society · 2020
    Pooled it
  8. Pooled it
  9. Review
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  11. Review
  12. Article
  13. Impact of COVID-19 in solid organ transplant recipients.American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons · 2021
    Review
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  16. Observational
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  20. SARS-CoV2 and immunosuppression: A double-edged sword.Transplant infectious disease : an official journal of the Transplantation Society · 2020
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Jeffrey J HsuDivision of Cardiology, Department of Medicine, David Geffen School of Medicine at UCLA, Los Angeles, California, USA.ORCID https://orcid.org/0000-0002-9971-5916
Pryce GaynorHeart Transplant Program, Department of Medicine, David Geffen School of Medicine at UCLA, Los Angeles, California, USA.
Megan KamathDivision of Cardiology, Department of Medicine, David Geffen School of Medicine at UCLA, Los Angeles, California, USA.
Ashley FanDivision of Cardiology, Department of Medicine, David Geffen School of Medicine at UCLA, Los Angeles, California, USA.ORCID https://orcid.org/0000-0002-8952-6548
Farah Al-SaffarDivision of Cardiology, Department of Medicine, David Geffen School of Medicine at UCLA, Los Angeles, California, USA.
Daniel CruzDivision of Cardiology, Department of Medicine, David Geffen School of Medicine at UCLA, Los Angeles, California, USA.
Ali NsairDivision of Cardiology, Department of Medicine, David Geffen School of Medicine at UCLA, Los Angeles, California, USA.
University of California, Los Angeles · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is rapidly infecting people worldwide, resulting in the infectious disease coronavirus disease 19 (COVID-19) that has been declared a pandemic. Much remains unknown about COVID-19, including its effects on solid organ transplant (SOT) recipients. Given their immunosuppressed state, SOT recipients are presumed to be at high risk of complications with viral infections such as SARS-CoV-2. Limited case reports in single SOT recipients, however, have not suggested a particularly severe course in this population. In this report, we present a dual-organ (heart/kidney) transplant recipient who was found to have COVID-19 and, despite the presence of a number of risk factors for poor outcomes, had a relatively mild clinical course.

Indexed as

Heart TransplantationKidney TransplantationAdenosine MonophosphateAdultAlanineBetacoronavirusCardiomyopathy, DilatedCoronavirus InfectionsCOVID-19HumansHydroxychloroquineImmunocompromised HostImmunosuppression TherapyImmunosuppressive AgentsKidney Failure, ChronicMaleAdenosine MonophosphateAlanineHydroxychloroquineImmunosuppressive Agentsremdesivirbiomarkerclinical research/practicediabetes: type 2graft survivalheart transplantation/cardiologyimmunosuppressive regimens - minimization/withdrawalinfection and infectious agents - viralinfectious diseasekidney transplantation/nephrology

Identifiers

PMID32315122
PMCPMC7264582
OpenAlexW3016413978

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.