Evidence map›Paper›PMID 32314805›Full record

SynthesisJournal of medical virology2020

CT imaging features of 4121 patients with COVID-19: A meta-analysis.

Jieyun Zhu, Zhimei Zhong, Hongyuan Li, Pan Ji, Jielong Pang, Bocheng Li, Jianfeng Zhang

Abstract readMeta-Analysis
In one paragraph

Synthesis in Journal of medical virology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 65 papers, 9 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
65citing papers in PubMed, 9 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

65 citing papers in PubMed, 9 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Pooled it
  5. Chest CT abnormalities in COVID-19: a systematic review.International journal of medical sciences · 2021
    Pooled it
  6. Pooled it
  7. Pooled it
  8. Pooled it
  9. Pooled it
  10. Review
  11. Article
  12. Article
  13. Review
  14. Observational
  15. Article
  16. Article
  17. Article
  18. AI for COVID-19 Detection from Radiographs: Incisive Analysis of State of the Art Techniques, Key Challenges and Future Directions.Ingenierie et recherche biomedicale : IRBM = Biomedical engineering and research · 2022
    Review
  19. Review
  20. Article

5 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Jieyun ZhuDepartment of Emergency, The Second Affiliated Hospital of Guangxi Medical University, Nanning, China.
Zhimei ZhongDepartment of Emergency, The Second Affiliated Hospital of Guangxi Medical University, Nanning, China.
Hongyuan LiDepartment of Emergency, The Second Affiliated Hospital of Guangxi Medical University, Nanning, China.
Pan JiDepartment of Emergency, The Second Affiliated Hospital of Guangxi Medical University, Nanning, China.
Jielong PangDepartment of Emergency, The Second Affiliated Hospital of Guangxi Medical University, Nanning, China.
Bocheng LiDepartment of Emergency, The Second Affiliated Hospital of Guangxi Medical University, Nanning, China.ORCID 0000-0002-3174-1595
Jianfeng ZhangDepartment of Emergency, The Second Affiliated Hospital of Guangxi Medical University, Nanning, China.ORCID 0000-0003-4213-9310

Funding

The Emergency Science and Technology Brainstorm Project for the Prevention and Control of COVID-19, which is part of the Guangxi Key Research and Development Plan (2020AB39028).The National Natural Science Foundation of China 81960343
6 · The paper itself

Abstract

objectiveWe systematically reviewed the computed tomography (CT) imaging features of coronavirus disease 2019 (COVID-19) to provide reference for clinical practice.

methodsOur article comprehensively searched PubMed, FMRS, EMbase, CNKI, WanFang databases, and VIP databases to collect literatures about the CT imaging features of COVID-19 from 1 January to 16 March 2020. Three reviewers independently screened literature, extracted data, and assessed the risk of bias of included studies, and then, this meta-analysis was performed by using Stata12.0 software.

resultsA total of 34 retrospective studies involving a total of 4121 patients with COVID-19 were included. The results of the meta-analysis showed that most patients presented bilateral lung involvement (73.8%, 95% confidence interval [CI]: 65.9%-81.1%) or multilobar involvement (67.3%, 95% CI: 54.8%-78.7%) and just little patients showed normal CT findings (8.4%). We found that the most common changes in lesion density were ground-glass opacities (68.1%, 95% CI: 56.9%-78.2%). Other changes in density included air bronchogram sign (44.7%), crazy-paving pattern (35.6%), and consolidation (32.0%). Patchy (40.3%), spider web sign (39.5%), cord-like (36.8%), and nodular (20.5%) were common lesion shapes in patients with COVID-19. Pleural thickening (27.1%) was found in some patients. Lymphadenopathy (5.4%) and pleural effusion (5.3%) were rare.

conclusionThe lung lesions of patients with COVID-19 were mostly bilateral lungs or multilobar involved. The most common chest CT findings were patchy and ground-glass opacities. Some patients had air bronchogram, spider web sign, and cord-like. Lymphadenopathy and pleural effusion were rare.

Indexed as

PandemicsBetacoronavirusBiomarkersChinaClinical Laboratory TechniquesCoronavirus InfectionsCOVID-19COVID-19 TestingHumansLungLymphadenopathyPleural EffusionPneumonia, ViralRetrospective StudiesSARS-CoV-2Severity of Illness IndexBiomarkerscomputed tomographycoronavirus disease 2019imaging featuresmeta-analysispneumoniasystematical review

Identifiers

PMID32314805
PMCPMC7264580

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.