ArticleThe American journal of tropical medicine and hygiene2020
Is Malaria an Important Cause of Death among Adults?
Article in The American journal of tropical medicine and hygiene, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
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Who cites it
9 citing papers in PubMed.
- Exploring factors affecting malaria vaccination intention and COVID-19 vaccine uptake: evidence from a joint analysis in rural Senegal.BMC public health · 2026Article
- Integrated Serosurveillance of Infectious Diseases Using Multiplex Bead Assays: A Systematic Review.Tropical medicine and infectious disease · 2025Review
- Unlocking the potential of novel RTS, S/AS01, and R21/Matrix-M™ malaria vaccines in African nations.Health science reports · 2024Article
- Could vaccinating adults against malaria materially reduce adult mortality in high-transmission areas?Malaria journal · 2023Review
- Current advances in nanodrug delivery systems for malaria prevention and treatment.Discover nano · 2023Review
- Adult malaria mortality during 2019 at Bo Government Hospital, Sierra Leone.Gates open research · 2023Article
- Spatio-temporal modelling of malaria mortality in India from 2004 to 2013 from the Million Death Study.Malaria journal · 2022Article
- Child, maternal, and adult mortality in Sierra Leone: nationally representative mortality survey 2018-20.The Lancet. Global health · 2022Article
- Accuracy of verbal autopsy, clinical data and minimally invasive autopsy in the evaluation of malaria-specific mortality: an observational study.BMJ global health · 2021Observational
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Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
A long-held assumption has been that nearly all malaria deaths in high-transmission areas are of children younger than 5 years and pregnant women. Most global malaria mortality estimates incorporate this assumption in their calculations. In 2010, the Indian Million Death Study, which assigns cause of death by verbal autopsy (VA), challenged the reigning perception, producing a U-shaped mortality age curve, with rates rising after age 45 years in areas of India with substantial malaria transmission. Similar patterns are seen in Africa in the International Network for the Demographic Evaluation of Populations and Their Health (INDEPTH) network, also relying on VA. Whether these results are accurate or are misidentified deaths can be resolved by improving the evidence for assigning causes for adult acute infectious deaths in high malaria transmission areas. The options for doing so include improving the accuracy of VA and adding postmortem biological evidence, steps we believe should be initiated without delay.
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