Evidence map›Paper›PMID 32314608›Full record

ArticleJournal of enzyme inhibition and medicinal chemistry2020

Bacterial ι-carbonic anhydrase: a new active class of carbonic anhydrase identified in the genome of the Gram-negative bacterium

Sonia Del Prete, Alessio Nocentini, Claudiu T Supuran, Clemente Capasso

Open access · goldAbstract read
In one paragraph

Article in Journal of enzyme inhibition and medicinal chemistry, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 51 papers.

0numbers the graph read from it
0cells of the map it votes in
51citing papers in PubMed
6.4field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

51 citing papers in PubMed, 97 citations in OpenAlex.

  1. Article
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  9. Selected strategies to fight pathogenic bacteria.Journal of enzyme inhibition and medicinal chemistry · 2023
    Review
  10. Article
  11. Article
  12. Article
  13. Direct Biocatalytic Processes for COMolecules (Basel, Switzerland) · 2023
    Review
  14. Article
  15. Review
  16. Review
  17. Review
  18. Structure-activity relationship studies for inhibitors for vancomycin-resistantJournal of enzyme inhibition and medicinal chemistry · 2022
    Article
  19. Activation studies with amino acids and amines of a β-carbonic anhydrase fromJournal of enzyme inhibition and medicinal chemistry · 2022
    Article
  20. Repurposing FDA-approved sulphonamide carbonic anhydrase inhibitors for treatment ofJournal of enzyme inhibition and medicinal chemistry · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Sonia Del PreteDepartment of Biology, Agriculture and Food Sciences, Institute of Biosciences and Bioresources, CNR, Napoli, Italy.
Alessio NocentiniDepartment of NEUROFARBA, University of Florence, Section of Pharmaceutical and Nutraceutical Sciences, Firenze, Italy.
Claudiu T SupuranDepartment of NEUROFARBA, University of Florence, Section of Pharmaceutical and Nutraceutical Sciences, Firenze, Italy.ORCID http://orcid.org/0000-0003-4262-0323
Clemente CapassoDepartment of Biology, Agriculture and Food Sciences, Institute of Biosciences and Bioresources, CNR, Napoli, Italy.ORCID http://orcid.org/0000-0003-3314-2411
Institute of Biosciences and Bioresources · ITUniversity of Florence · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The carbonic anhydrases (CAs, EC 4.2.1.1) catalyse a simple but physiologically crucial reversible reaction, the carbon dioxide hydration with the production of bicarbonate and protons. In the last years, and especially, to the rapid emergence of the bacterial antibiotic resistance that is occurring worldwide, the understanding of the function of bacterial CAs has increased significantly. Recently, a new CA-class (ι-CA) was discovered in the marine diatom

Indexed as

AcetazolamideAmino Acid SequenceBurkholderiaCarbonic Anhydrase InhibitorsCarbonic AnhydrasesDose-Response Relationship, DrugModels, MolecularMolecular StructurePhylogenyRecombinant ProteinsStructure-Activity RelationshipSulfonamidesAcetazolamideCarbonic Anhydrase InhibitorsCarbonic AnhydrasesRecombinant ProteinsSulfonamidesbacterial CABurkholderia territoriiCarbonic anhydrasecatalytic ion cofactorhydratase activityiota-CA

Identifiers

PMID32314608
PMCPMC7191908
OpenAlexW3017340976

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.