ArticleJournal of biomedical optics2020
Low-cost, ultracompact handheld optical coherence tomography probe for in vivo oral maxillofacial tissue imaging.
Article in Journal of biomedical optics, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
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Who cites it
13 citing papers in PubMed, 30 citations in OpenAlex.
- Volumetric Imaging of Ex Vivo Oral Mucosa Specimens with Multi-Scale Wide Field-of-View Optical Coherence Tomography/Microscopy in Near-Infrared-II Window.Diagnostics (Basel, Switzerland) · 2026Article
- Accurate and timely intraoperative classification of vocal cord leukoplakia by machine learning assisted handheld OCT.Biomedical optics express · 2025Article
- Development of next generation low-cost OCT towards improved point-of-care retinal imaging.Biomedical optics express · 2025Article
- A Precessing-Coin-like Rotary Actuator for Distal Endoscope Scanners: Proof-of-Concept Study.Micromachines · 2025Article
- A Novel Small Form-Factor Handheld Optical Coherence Tomography Probe for Oral Soft Tissue Imaging.Micromachines · 2024Article
- Next-generation endoscopic probe for detection of esophageal dysplasia using combined OCT and angle-resolved low-coherence interferometry.Biomedical optics express · 2024Article
- Wearable optical coherence tomography angiography probe for freely moving mice.Biomedical optics express · 2023Article
- Large Area Kidney Imaging for Pre-transplant Evaluation using Real-Time Robotic Optical Coherence Tomography.Research square · 2023Article
- Deep-Learning-Based Automated Identification and Visualization of Oral Cancer in Optical Coherence Tomography Images.Biomedicines · 2023Article
- Label-Free Metabolic Imaging In Vivo by Two-Photon Fluorescence Lifetime Endomicroscopy.ACS photonics · 2022Article
- Intraoral optical coherence tomography and angiography combined with autofluorescence for dental assessment.Biomedical optics express · 2022Article
- Classification of oral salivary gland tumors based on texture features in optical coherence tomography images.Lasers in medical science · 2022Article
- A review of low-cost and portable optical coherence tomography.Progress in biomedical engineering (Bristol, England) · 2021Article
Corrections and comments
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Authors and funding
6 authors at 4 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
significanceOptical coherence tomography (OCT) has proven useful for detecting various oral maxillofacial abnormalities. To apply it to clinical applications including biopsy guidance and routine screening, a handheld imaging probe is indispensable. OCT probes reported for oral maxillofacial imaging were either based on a bulky galvanometric mirror pair (not compact or long enough) or a distal-end microelectromechanical systems (MEMS) scanner (raised safety concerns), or adapted from fiber-optic catheters (ill-suited for oral cavity geometry).
aimTo develop a handheld probe featuring great compactness and excellent maneuverability for oral maxillofacial tissue imaging. APPROACH: A dual-axis MEMS scanner was deployed at the proximal end of the probe and the scanned beam was relayed to the distal end through a 4f configuration. Such design provides both a perfect dual-axis telecentric scan and excellent compactness.
resultsA handheld probe with a rigid part 70 mm in length and 7 mm in diameter and weighing 25 g in total was demonstrated through both ex vivo and in vivo experiments, including structural visualization of various oral maxillofacial tissues and monitoring the recovery process of an oral mucosa canker sore.
conclusionsThe proposed probe exhibits excellent maneuverability and imaging performance showing great potential in clinical applications.
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