ReviewDevelopmental dynamics : an official publication of the American Association of Anatomists2020
Wound healing across the animal kingdom: Crosstalk between the immune system and the extracellular matrix.
Review in Developmental dynamics : an official publication of the American Association of Anatomists, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 40 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
40 citing papers in PubMed, 73 citations in OpenAlex.
- Xylazine, veterinary anesthetic and recreational drug adulterant, reduces cephalic regeneration and alters defensive responding in planarians.Neurotoxicology · 2026Article
- An iontronic reservoir for highly robust neuromorphic prosthesis.Nature materials · 2026Article
- Comparative Wound Healing Processes in Plants and Animals: Bioinspired Strategies for Advancing Regenerative Medicine.International journal of molecular sciences · 2026Review
- Discovery of an Adaptive Neuroimmune Response Driving Itch and Fast Tick Removal with Implications for Preventing Pathogen Transmission.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026Article
- Longitudinal multimodal assessment of neuropathy in a porcine neuritis model.Journal of neuroscience methods · 2026Article
- Segment Regeneration of an Earthworm I: Formation of the Body Wall Tissues from Injury to Recovery.Life (Basel, Switzerland) · 2026Article
- Axolotl-derived decellularized skin ECM as a pro-regenerative scaffold for attenuating fibrotic wound healing.Materials today. Bio · 2025Article
- Wound-induced eyespots on butterfly wings at the intersection of immune response and pigmentation development.BMC biology · 2025Article
- Discovery of an Adaptive Neuroimmune Response Driving Itch and Fast Tick Removal with Implications for Preventing Pathogen Transmission.bioRxiv : the preprint server for biology · 2025Article
- Reimagining Fibrosis Research, Outcomes, and Therapeutics Through the Lens of Resolution.Seminars in respiratory and critical care medicine · 2025Review
- Neuronal activation in the axolotl brain promotes tail regeneration.NPJ Regenerative medicine · 2025Article
- Revealing shared molecular and mechanistic signatures between intracranial aneurysms and abdominal aortic aneurysms: a comprehensive genomic analysis.Orphanet journal of rare diseases · 2025Article
- Article
- Non-invasive physical plasma improves conventional wound management of cut and bite wounds in wild European hedgehogs.Scientific reports · 2025Article
- Enhancing the wound healing potential using earthworm clitellum factors and elucidating its molecular mechanism in an in-vitro and earthworm model.Scientific reports · 2024Article
- Characterization of regeneration initiating cells during Xenopus laevis tail regeneration.Genome biology · 2024Article
- The brittle star genome illuminates the genetic basis of animal appendage regeneration.Nature ecology & evolution · 2024Article
- Collagen in the central nervous system: contributions to neurodegeneration and promise as a therapeutic target.Molecular neurodegeneration · 2024Review
- Adipose-derived Mesenchymal Stem Cells are Ideal for the Cell-based Treatment of Refractory Wounds: Strong Potential for Angiogenesis.Stem cell reviews and reports · 2024Article
- Highly hydrophilic and dispersed TiOJournal of nanobiotechnology · 2023Article
Corrections and comments
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Authors and funding
3 authors at 1 institution in 1 country.
Funding
Abstract
Tissue regeneration is widespread in the animal kingdom. To date, key roles for different molecular and cellular programs in regeneration have been described, but the ultimate blueprint for this talent remains elusive. In animals capable of tissue regeneration, one of the most crucial stages is wound healing, whose main goal is to close the wound and prevent infection. In this stage, it is necessary to avoid scar formation to facilitate the activation of the immune system and remodeling of the extracellular matrix, key factors in promoting tissue regeneration. In this review, we will discuss the current state of knowledge regarding the role of the immune system and the interplay with the extracellular matrix to trigger a regenerative response.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.