Evidence map›Paper›PMID 32314379›Full record

ArticleJournal of anatomy2020

Neuronal volume of the hippocampal regions in ageing.

José Carlos Delgado-González, Carlos de la Rosa-Prieto, Diana Lucía Tarruella-Hernández, Nuria Vallejo-Calcerrada, Sandra Cebada-Sánchez, Ricardo Insausti, Emilio Artacho-Pérula

Open access · bronzeAbstract read
In one paragraph

Article in Journal of anatomy, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.7field-weighted citation impact, top 34% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 8 citations in OpenAlex.

  1. Article
  2. Frontiers in neuroanatomy · 2023
    Article
  3. Cellular enlargement - A new hallmark of aging?Frontiers in cell and developmental biology · 2022
    Review
  4. Review
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

José Carlos Delgado-González *Human Neuroanatomy Laboratory, School of Medicine, University of Castilla-La Mancha, Albacete, Spain.
Carlos de la Rosa-Prieto *Human Neuroanatomy Laboratory, School of Medicine, University of Castilla-La Mancha, Albacete, Spain.ORCID 0000-0003-1644-1735
Diana Lucía Tarruella-HernándezHuman Neuroanatomy Laboratory, School of Medicine, University of Castilla-La Mancha, Albacete, Spain.
Nuria Vallejo-CalcerradaHuman Neuroanatomy Laboratory, School of Medicine, University of Castilla-La Mancha, Albacete, Spain.
Sandra Cebada-SánchezNursing School, University of Castilla-La Mancha, Albacete, Spain.ORCID 0000-0001-9547-9277
Ricardo InsaustiHuman Neuroanatomy Laboratory, School of Medicine, University of Castilla-La Mancha, Albacete, Spain.ORCID 0000-0001-6610-5882
Emilio Artacho-PérulaHuman Neuroanatomy Laboratory, School of Medicine, University of Castilla-La Mancha, Albacete, Spain.ORCID 0000-0002-2201-576X
University of Castilla-La Mancha · ES

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The hippocampal formation (HF) has an important role in different human capacities, such as memory processing and emotional expression. Both extensive changes and limited variations of its components can cause clinically expressed dysfunctions. Although there remains no effective treatment for diseases caused by pathological changes in this brain region, detection of these changes, even minimally, could allow us to develop early interventions and establish corrective measures. This study analysed the neuronal islands of layer II of the entorhinal cortex (EC), the neuronal clumps of the external principal layer of the presubiculum (PrS) and the dentate granule cells of the dentate gyrus (DG), which represent the prominent structural regions within the HF circuit. Subjects from two age groups (younger or older than 65 years) were studied and their neuronal size assessed by the point-sampled intercepts stereological method. The quantitative

Indexed as

AdultAgedAged, 80 and overAgingCell SizeFemaleHippocampusHumansMaleMiddle AgedNeuronsYoung Adultageingdentate gyrusentorhinal cortexhuman hippocampal formationpoint-sampled intercepts methodpresubiculumstereology

Identifiers

PMID32314379
PMCPMC7369192
OpenAlexW3016999327

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.