ArticleBrain imaging and behavior2021
Altered white matter structural networks in drug-naïve patients with obsessive-compulsive disorder.
Article in Brain imaging and behavior, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
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Who cites it
7 citing papers in PubMed.
- Disruption of functional and structural topological organization in specific subnetwork among patients with classical trigeminal neuralgia: a graph theory-based magnetic resonance imaging study.Brain imaging and behavior · 2025Article
- Age of onset of obsessive-compulsive disorder differentially affects white matter microstructure.Molecular psychiatry · 2024Article
- Aberrant brain topological organization and granger causality connectivity in Parkinson's disease with impulse control disorders.Frontiers in aging neuroscience · 2024Article
- Structural alterations of the salience network in patients with insular glioma.Brain and behavior · 2023Article
- Abnormal white-matter rich-club organization in obsessive-compulsive disorder.Human brain mapping · 2022Article
- Convergent and Divergent Structural Connectivity of Brain White Matter Network Between Patients With Erectile Dysfunction and Premature Ejaculation: A Graph Theory Analysis Study.Frontiers in neurology · 2022Article
- White Matter Structural Network Analysis to Differentiate Alzheimer's Disease and Subcortical Ischemic Vascular Dementia.Frontiers in aging neuroscience · 2021Article
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Authors and funding
10 authors.
Funding
Abstract
White matter (WM) alteration is considered to be a vital neurological mechanism of obsessive-compulsive disorder (OCD). However, little is known regarding the changes in topological organization of WM structural network in OCD. We acquired diffusion tensor imaging (DTI) datasets from 28 drug-naïve OCD patients and 28 well-matched healthy controls (HC). A deterministic fiber tracking approach was used to construct the whole-brain structural connectome. Group differences in global and nodal topological properties as well as rich-club organizations were compared by using graph theory analysis. The relationship between the altered network metrics and the Yale-Brown Obsessive-Compulsive Scale (Y-BOCS) was calculated. Compared with controls, OCD patients exhibited a significantly decreased small-worldness (σ), normalized clustering coefficient (γ) and shortest path length (L
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