Evidence map›Paper›PMID 32314120›Full record

Trial reportAIDS and behavior2020

Retention in HIV Care Among HIV-Seropositive Pregnant and Postpartum Women in Uganda: Results of a Randomized Controlled Trial.

Lora L Sabin, Nafisa Halim, Davidson H Hamer, Elizabeth M Simmons, Sivani Jonnalagadda, Anna Larson Williams, Harriet Chemusto, Allen L Gifford, Rachael Bonawitz, Philip Aroda and 4 more

Abstract readRandomized Controlled Trial
PubMed Publisher
In one paragraph

Trial report in AIDS and behavior, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed, 4 pooled it
0.4field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 4 syntheses or guidelines pooled it, 22 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 5 institutions in 2 countries.

Lora L SabinDepartment of Global Health, Boston University School of Public Health, 801 Massachusetts Avenue, Crosstown Center, 3rd Floor, Boston, MA, 02118, USA. lsabin@bu.edu.
Nafisa HalimDepartment of Global Health, Boston University School of Public Health, 801 Massachusetts Avenue, Crosstown Center, 3rd Floor, Boston, MA, 02118, USA.
Davidson H HamerDepartment of Global Health, Boston University School of Public Health, 801 Massachusetts Avenue, Crosstown Center, 3rd Floor, Boston, MA, 02118, USA.
Elizabeth M SimmonsDepartment of Global Health, Boston University School of Public Health, 801 Massachusetts Avenue, Crosstown Center, 3rd Floor, Boston, MA, 02118, USA.
Sivani JonnalagaddaDepartment of Global Health, Boston University School of Public Health, 801 Massachusetts Avenue, Crosstown Center, 3rd Floor, Boston, MA, 02118, USA.
Anna Larson WilliamsDepartment of Global Health, Boston University School of Public Health, 801 Massachusetts Avenue, Crosstown Center, 3rd Floor, Boston, MA, 02118, USA.
Harriet ChemustoMildmay Uganda, Kampala, Uganda.
Allen L GiffordCenter for Healthcare Organization and Implementation Research, VA Boston Healthcare System, Boston, MA, USA.
Rachael BonawitzDepartment of Global Health, Boston University School of Public Health, 801 Massachusetts Avenue, Crosstown Center, 3rd Floor, Boston, MA, 02118, USA.
Philip ArodaMildmay Uganda, Kampala, Uganda.
Mary DeSilvaWestbrook College of Health Professions, University of New England, Portland, ME, USA.
Julia GasuzaMildmay Uganda, Kampala, Uganda.
Barbara MukasaMildmay Uganda, Kampala, Uganda.
Lisa J MessersmithDepartment of Global Health, Boston University School of Public Health, 801 Massachusetts Avenue, Crosstown Center, 3rd Floor, Boston, MA, 02118, USA.
Boston University · USMildmay Uganda · UGNew England College · USSt. Christopher's Hospital for Children · USVA Boston Healthcare System · US

Funding

Improving ART Retention and Adherence in Uganda, the WiseMama StudyR34MH103075 · NIMH · BOSTON UNIVERSITY MEDICAL CAMPUS · PI MESSERSMITH, LISA JEAN, SABIN, LORA L · 2014 to 2016
$670k
China Adherence through Technology Study (CATS)R34DA032423 · NIDA · BOSTON UNIVERSITY MEDICAL CAMPUS · PI SABIN, LORA L · 2012 to 2014
$670k
NIDA NIH HHS R34 DA032423NIMH NIH HHS 1R34MN103075
6 · The paper itself

Abstract

We tested an intervention that aimed to increase retention in antiretroviral therapy (ART) among HIV-positive pregnant and postpartum women, a population shown to be vulnerable to poor ART outcomes. 133 pregnant women initiating ART at 2 hospitals in Uganda used real time-enabled wireless pill monitors (WPM) for 1 month, and were then randomized to receive text message reminders (triggered by late dose-taking) and data-informed counseling through 3 months postpartum or standard care. We assessed "full retention" (proportion attending all monthly clinic visits and delivering at a study facility; "visit retention" (proportion of clinic visits attended); and "postpartum retention" (proportion retained at 3 months postpartum). Intention-to-treat and per protocol analyses found that retention was relatively low and similar between groups, with no significant differences. Retention declined significantly post-delivery. The intervention was unsuccessful in this population, which experiences suboptimal ART retention and is in urgent need of effective interventions.

Indexed as

Retention in CareAdultAnti-HIV AgentsCounselingFemaleHIV InfectionsHumansPatient Acceptance of Health CarePostpartum PeriodPregnancyPregnancy Complications, InfectiousPregnant PeopleTreatment OutcomeUgandaAnti-HIV AgentsClinical trialsPregnant womenRetention in HIV careUganda

Identifiers

PMID32314120
OpenAlexW3016353505

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.