ArticleInternational journal of legal medicine2020
Development of an NGS panel containing 42 autosomal STR loci and the evaluation focusing on secondary kinship analysis.
Article in International journal of legal medicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 1 of them a synthesis that pooled it.
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Who cites it
11 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Bibliometric analysis of kinship analysis from 1960 to 2023: global trends and development.Frontiers in genetics · 2024Pooled it
- Forensic utilization of NGS-STRs and evaluation of system efficacy for different kinship identifications.Human genomics · 2025Article
- Improved second-degree kinship analysis using the FGID forensic four-in-one DNA typing kit.International journal of legal medicine · 2025Article
- Parallel sequencing of 170 STR and 132 SNP markers using the FGID forensic four-in-one DNA typing kit on the DNBSEQ-G99RS platform.Forensic sciences research · 2025Article
- Systematically improving the efficiency of complex kinship identification through the addition of genetic markers and reference individuals.International journal of legal medicine · 2025Article
- Complex kinship testing using the MGIEasy Pa-SNPs genotyping kit.International journal of legal medicine · 2025Article
- An approach to unified formulae for likelihood ratio calculation in pairwise kinship analysis.Frontiers in genetics · 2024Article
- Recent advances in forensic biology and forensic DNA typing: INTERPOL review 2019-2022.Forensic science international. Synergy · 2023Article
- Development and validation of a novel 133-plex forensic STR panel (52 STRs and 81 Y-STRs) using single-end 400 bp massive parallel sequencing.International journal of legal medicine · 2022Article
- Forensic Feature Exploration and Comprehensive Genetic Insights Into Yugu Ethnic Minority and Northern Han PopulationFrontiers in genetics · 2022Article
- Developmental validation of the MGIEasy Signature Identification Library Prep Kit, an all-in-one multiplex system for forensic applications.International journal of legal medicine · 2021Article
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Authors and funding
9 authors.
Funding
Abstract
High-throughput next-generation sequencing (NGS) is a feasible technique to detect considerably more markers and simultaneously obtain length and sequence information in a single reaction. In this study, we developed an NGS panel including 42 commonly used autosomal short tandem repeats (STRs) and amelogenin on the Illumina MiSeq FGx™. Sequencing accuracy was validated by the consistency of 2800M Control DNA detected using the ForenSeq™ DNA Signature Prep Kit and Sanger sequencing. Nomenclature incompatibility was found between NGS-STR and CE-STR typing at 9 loci (D3S3045, D6S477, D7S3048, D9S925, D14S608, D17S1290, D18S535, D21S1270, GATA198B05), despite the correct sequence. The difference was caused by the two different methods of identifying motif sequence and a one-to-one correspondence can be found. We evaluated the panel by investigating consistency, sequencing sensitivity and the effectiveness of the 2nd-degree relationship identification. Herein, we present sequencing results from 58 unrelated individuals of the Hebei Han population. The total discrimination power (TDP) and cumulative probability of exclusion for trio paternity testing (CPE
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