Evidence map›Paper›PMID 32314022›Full record

ArticleMikrochimica acta2020

Optical assay of trypsin using a one-dimensional plasmonic grating of gelatin-modified poly(methacrylic acid).

Ai-Wei Lee, Chih-Chia Cheng, Chi-Jung Chang, Chien-Hsing Lu, Jem-Kun Chen

Abstract read
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In one paragraph

Article in Mikrochimica acta, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.2field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 15 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Plasmonic Gold Nanoisland Film for Bacterial Theranostics.Nanomaterials (Basel, Switzerland) · 2021
    Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 1 country.

Ai-Wei LeeDepartment of Anatomy and Cell Biology, School of Medicine, College of Medicine, Taipei Medical University, Taipei, 110, Taiwan.
Chih-Chia ChengAdvanced Membrane Materials Research Centre, Graduate Institute of Applied Science and Technology, National Taiwan University of Science and Technology, 43, Sec. 4, Keelung Road, Taipei, 10607, Taiwan, Republic of China.
Chi-Jung ChangDepartment of Chemical Engineering, Feng Chia University, 100, Wenhwa Road, Seatwen, Taichung, 40724, Taiwan, Republic of China.
Chien-Hsing LuDepartment of Obstetrics and Gynecology, Taichung Veterans General Hospital, Taichung, Taiwan, Republic of China. jkchen@mail.ntust.edu.tw.
Jem-Kun ChenDepartment of Materials Science and Engineering, National Taiwan University of Science and Technology, 43, Sec. 4, Keelung Road, Taipei, 106, Taiwan, Republic of China. chlu@vghtc.gov.tw.ORCID https://orcid.org/0000-0003-3670-6710
National Taiwan University of Science and Technology · TWFeng Chia University · TWNational Yang Ming Chiao Tung University · TW

Funding

Ministry of Science and Technology, Taiwan 106-2221-E-011-135-MY3
6 · The paper itself

Abstract

The geometry of resonant absorbers (RA) is varied by tryptic digestion to design a probe platform. The process includes fabrication of a line array of poly(methacrylic acid) (PMAA) brush as an RA, tailed by the immobilization of gelatin. The gelatin-modified PMAA RA is a kind of one-dimensional plasmonic grating, possessing an optical feature with a characteristic absorption peak. The growth of gelatin on PMAA RA resulted in a blue shift of the absorption peak from 465 to 263 nm. Trypsin catalyzes the hydrolysis of peptide bonds, breaking down gelatin into smaller peptides causing the change in geometry of RA. The gelatin of RA was digested in a wide linear range of activity of trypsin from 34 to 1088 U mL

Indexed as

Atom transfer radical polymerizationDiffuse reflection spectroscopyGastrointestinal diseasesPolymer brushStripe pattern

Identifiers

PMID32314022
OpenAlexW3016346274

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.