SynthesisActa diabetologica2020
Effects of plant protein and animal protein on lipid profile, body weight and body mass index on patients with hypercholesterolemia: a systematic review and meta-analysis.
Synthesis in Acta diabetologica, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers, 3 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
24 citing papers in PubMed, 3 syntheses or guidelines pooled it, 43 citations in OpenAlex.
- Long-term effects of plant vs. animal protein supplementation on body composition, muscle strength, physical performance, and cardiometabolic risk factors in adults:a systematic review and meta-analysis of randomized controlled trials.Frontiers in nutrition · 2026Pooled it
- Pooled it
- Protein intake and body weight, fat mass and waist circumference: an umbrella review of systematic reviews for the evidence-based guideline on protein intake of the German Nutrition Society.European journal of nutrition · 2024Pooled it
- Effects of Dietary Protein Quantity, Source, and Type on Plasma Lipids and Lipoproteins and Their Roles in Dyslipidemia Management in Humans.Nutrients · 2026Review
- Association of macronutrient quality at dinner versus breakfast with body composition in adults living in Tehran: results from a cross-sectional study.BMC nutrition · 2026Article
- Association between dietary patterns and biological aging among Chinese middle-aged and older adults: evidence from a cross-sectional study.Frontiers in nutrition · 2026Article
- Optimal Intake of Animal-Source Foods: A Scoping Review to Inform a New WHO Guideline.Advances in nutrition (Bethesda, Md.) · 2025Article
- Protein, fiber, and exercise: a narrative review of their roles in weight management and cardiometabolic health.Lipids in health and disease · 2025Review
- Plant-Based vs. Animal-Based Diets: Appetitive Traits and Dietary Patterns in Adults Based on Cross-Sectional Surveys.Nutrients · 2025Article
- The Association Between Dietary Protein Intake and Gallstone Disease: A Case-Control Study.Gastroenterology research and practice · 2025Article
- The VEGPREV study: effectiveness of four plant-based diets on weight loss, metabolic syndrome components and appetitive traits in overweight and obese individuals: a randomized controlled trial.Frontiers in nutrition · 2025Article
- Article
- Association between diet protein score comprising plants to animal protein ratio and body composition in an Iranian population.Scientific reports · 2024Article
- Phytochemical Analysis and Antioxidant Activities of Various Extracts from the Aerial Part ofMolecules (Basel, Switzerland) · 2024Article
- Development strategy of non-GMO organism for increased hemoproteins in Corynebacterium glutamicum: a growth-acceleration-targeted evolution.Bioprocess and biosystems engineering · 2024Article
- Plant-based alternative proteins-are they nutritionally more advantageous?European journal of clinical nutrition · 2023Article
- Animal versus plant-based protein and risk of cardiovascular disease and type 2 diabetes: a systematic review of randomized controlled trials and prospective cohort studies.Food & nutrition research · 2023Review
- Article
- Evaluating type and amount of dietary protein in relation to metabolic syndrome among Iranian adults: cross-sectional analysis of Fasa Persian cohort study.Diabetology & metabolic syndrome · 2022Article
- A Scoping Review: Metabolomics Signatures Associated with Animal and Plant Protein Intake and Their Potential Relation with Cardiometabolic Risk.Advances in nutrition (Bethesda, Md.) · 2021Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveWe conducted a meta-analysis on the effect of plant protein or animal protein on body weight (BW), body mass index (BMI) and blood lipid profiles in patients with hypercholesterolemia. MATERIALS AND
methodsWe used subject and free words to search PubMed, Embase and Cochrane Library databases. The risk-of-bias evaluation tool was used to assess literature quality. Data merging and statistical analyses were carried out using Review Manager 5.3 and Stata 13.0. All indicators were expressed as the mean difference (MD) and 95% confidence interval (95% CI). The heterogeneity test was conducted according to I
resultsThis was a meta-analysis of intervention trials. Thirty-two studies (1562 patients) were included. The quality of the included studies was acceptable. Compared with consumption of animal protein, plant protein reduced total cholesterol (TC) (MD = - 0.19 mmol/L, 95% CI - 0.26, - 0.12), triglyceride (MD = - 0.07 mmol/L, 95% CI - 0.13, - 0.02), low-density lipoprotein cholesterol (LDL-C) (MD = - 0.19 mmol/L, 95% CI - 0.26, - 0.13), very low-density lipoprotein cholesterol (MD = - 0.05 mmol/L, 95% CI - 0.09, - 0.01), TC/LDL-C ratio (MD = - 0.17, 95% CI - 0.32, - 0.02) and LDL-C/HDL-C ratio (MD = - 0.20, 95% CI - 0.33, - 0.06) significantly and increased high-density lipoprotein cholesterol (HDL-C) (MD = 0.03 mmol/L, 95% CI 0.01, 0.06) levels, but had no effect on BW (MD = - 0.41 kg, 95% CI - 2.14, 1.33) or BMI (MD = 0.11 kg/m
conclusionCompared with animal protein, consumption of plant protein could improve lipid profile in patients with hypercholesterolemia.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.