ArticleGut pathogens2020
Molecular epidemiology of rotavirus A and adenovirus among children with acute diarrhea in Hangzhou, China.
Article in Gut pathogens, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
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Who cites it
18 citing papers in PubMed, 30 citations in OpenAlex.
- Epidemiological characteristics of rotavirus among children aged 5 years and under in Zhangzhou, China, 2023-2024.BMC infectious diseases · 2026Article
- Genetic diversity and phylogenetic characteristics of human adenovirus strains 40/41 circulating in Yantai, China, during 2017-2019.Applied and environmental microbiology · 2025Article
- Molecular epidemiology of viral enteric in children in Hangzhou.BMC infectious diseases · 2025Article
- Monitoring of Adenoviruses in Water and Wastewater through Applications of PCR Based Methods.Indian journal of microbiology · 2025Review
- Epidemic Characteristics, Spatiotemporal Pattern, and Risk Factors of Other Infectious Diarrhea in Fujian Province From 2005 to 2021: Retrospective Analysis.JMIR public health and surveillance · 2023Article
- Diverse genotypes of human enteric and non-enteric adenoviruses circulating in children hospitalized with acute gastroenteritis in Thailand, from 2018 to 2021.Microbiology spectrum · 2023Article
- Surveillance and epidemiological characterization of human adenovirus infections among outpatient children with acute gastroenteritis during the COVID-19 epidemic in Shanghai, China.Virology journal · 2023Article
- Prevalence and genotypes distribution of group A rotavirus among outpatient children under 5 years with acute diarrhea in Shanghai, China, 2012-2018.BMC gastroenterology · 2022Article
- Multiplex detection of eight different viral enteropathogens in clinical samples, combining RT-PCR technology with melting curve analysis.Virology journal · 2022Article
- Molecular epidemiological characteristics of the virus in 96 children with acute diarrhea in Changdu of Tibet, China.Zhongguo dang dai er ke za zhi = Chinese journal of contemporary pediatrics · 2022Article
- Viral metagenomics reveals diverse viruses in the fecal samples of children with diarrhea.Virologica Sinica · 2022Article
- Molecular Epidemiology of Human Adenovirus, Astrovirus, and Sapovirus Among Outpatient Children With Acute Diarrhea in Chongqing, China, 2017-2019.Frontiers in pediatrics · 2022Article
- Vaccination of pregnant rhesus monkeys with inactivated rotavirus as a model for achieving protection from rotavirus SA11 infection in the offspring.Human vaccines & immunotherapeutics · 2021Article
- Molecular and epidemiological characterization of human adenoviruses infection among children with acute diarrhea in Shandong Province, China.Virology journal · 2021Article
- Rotavirus and adenovirus infections in children during COVID-19 outbreak in Hangzhou, China.Translational pediatrics · 2021Article
- Review
- Epidemiological Trends and Hotspots of Other Infectious DiarrheaFrontiers in public health · 2021Article
- Genetic diversity of group A rotavirus in acute gastroenteritis outpatients in Shanghai from 2017 to 2018.BMC infectious diseases · 2020Article
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Authors and funding
6 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundRotavirus A (RVA) and adenovirus (Adv) are important causes of acute diarrhea in children. RVAs are classified into G and P genotypes based on viral proteins (VP)7 and VP4 gene and Adv contains over 70 genotypes based on hexon and fiber gene. This study aimed to characterize the molecular epidemiology of RVA and Adv in children with acute diarrhea during 2017-2018 in Hangzhou.
methodsThe stool samples were collected and tested for RVA and Adv by reverse transcription-quantitative PCR (RT-qPCR) assay. The RVA positive samples were detected by RT-PCR for VP7(G) and VP4([P]) genotypes, and the Adv positive samples were detected by PCR for genotyping by the target to hexon gene.
resultsAmong 228 RVA-positive samples, G9 was detected as the most frequent genotype (195/228, 85.5%), followed by G3 (20/228, 8.8%), G2 (7/228, 3.1%) and G1 (6/228, 2.6%). G9 strains were closely related to strains from China and neighboring countries, as well as the USA. On the other hand, P[8] strains were detected in 219 (96.1%) samples with most closely related to one strain from Malawi, and P[4] in 9 (3.9%) samples. G9P[8] (84.6%, 193/228) was the most prevalent rotavirus A strains, followed by G3P[8] (8.8%, 20/228), G2P[4] (3.1%, 7/228), G1P[8] (2.6%, 6/228) and G9P[4] (0.9%, 2/228). Of 167 Adv-positive cases, 2 different genotypes were identified with 152 (91.0%) of Adv-41and 15 (9%) of Adv-40. All Adv strains were closely related to prototype strains of Adv types 40 and 41 in India.
conclusionsG9P[8] of RVA and Adv-41 were the most common genotypes that caused children's acute diarrhea in Hangzhou, 2017-2018.
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