Evidence map›Paper›PMID 32313526›Full record

ArticleDose-response : a publication of International Hormesis Society

Expression of Caveolin-1 Is Associated With Thyroid Function in Patients With Human Papillary Thyroid Carcinoma.

Jingyi Zhang, Dongxia Yan, Lianping He, Qing Zhang, Shuang Wen, Peiyu Liu, Hong Zhou, Yongde Peng

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Dose-response : a publication of International Hormesis Society. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.1field-weighted citation impact, top 58% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 5 institutions in 1 country.

Jingyi ZhangDepartment of Endocrinology, Shanghai General Hospital of Nanjing Medical University, Shanghai, China.ORCID https://orcid.org/0000-0003-4083-6630
Dongxia YanDepartment of Pathology, Ma'anshan People's Hospital, Ma'anshan, China.
Lianping HeCollege of Experience Industry, Anhui Polytechnic University, Wuhu, Anhui, China.ORCID https://orcid.org/0000-0002-9627-5599
Qing ZhangDepartment of Pathology, Ma'anshan People's Hospital, Ma'anshan, China.
Shuang WenDepartment of Immunology, Nanjing Medical University, Nanjing, China.
Peiyu LiuDepartment of Pharmacology, School of Basic Medical Science, Nanjing Medical University, Nanjing, China.
Hong ZhouDepartment of Immunology, Nanjing Medical University, Nanjing, China.
Yongde PengDepartment of Endocrinology, Shanghai General Hospital of Nanjing Medical University, Shanghai, China.
Nanjing Medical University · CNAnshan Hospital · CNAnhui Polytechnic University · CNShanghai First People's Hospital · CNThird Affiliated Hospital of Guangzhou Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveThe aim of this study was to evaluate the levels of caveolin-1 in thyroid follicular epithelial cells of papillary thyroid cancer, follicular thyroid cancer, and nonmalignant thyroid nodule benign follicular adenoma, as well as to explore the relationship between the levels of caveolin-1 and thyroid function.

methodsThirty cases of papillary thyroid cancer, 10 cases of follicular thyroid cancer, 32 cases of nonmalignant thyroid nodule benign follicular adenoma, and 30 controls were enrolled in this study. Caveolin-1 expression in tissue specimens obtained from these cases was evaluated by immunohistochemistry and Western blotting.

resultsCaveolin-1 expression in thyroid epithelial cells of patients with papillary thyroid cancer, particularly female patients, was significantly higher than that in patients with follicular thyroid cancer and nonmalignant thyroid nodule benign follicular adenoma (

conclusionCaveolin-1 may participate in regulating thyroid function and is a potential biomarker of follicular thyroid cancer.

Indexed as

caveolin-1immunohistochemistrypapillary thyroid carcinomathyroid function

Identifiers

PMID32313526
PMCPMC7160781
OpenAlexW3016671848

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.