Evidence map›Paper›PMID 32313475›Full record

ArticleProceedings (Baylor University. Medical Center)2020

Human herpesvirus 6 meningitis in an adult.

Ganesh B Maniam, Hannah Wilkerson, John Scott Milton

Open access · greenAbstract readCase Reports
In one paragraph

Article in Proceedings (Baylor University. Medical Center), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.3field-weighted citation impact, top 42% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. Review
  3. HHV-6 Meningoencephalitis in a Healthy Adult Female.Case reports in emergency medicine · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Ganesh B ManiamSchool of Medicine, Texas Tech University Health Sciences CenterAmarilloTexas.ORCID 0000-0002-4217-9489
Hannah WilkersonSchool of Medicine, Texas Tech University Health Sciences CenterAmarilloTexas.
John Scott MiltonDepartment of Internal Medicine, Texas Tech University Health Sciences CenterAmarilloTexas.
Texas Tech University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Many cases of viral meningitis are idiopathic, but increased utilization of polymerase chain reaction testing has enabled physicians to better recognize rare causes of viral meningitis. This will likely continue to improve the rate of causative agent identification in seemingly idiopathic viral meningitis, including this case of human herpesvirus 6 (HHV-6) meningitis in an immunocompetent adult patient. More common viral etiologies need to be excluded before diagnosing HHV-6 meningitis, as this maximizes pretest probability and therefore increases validity of a positive result. By efficiently diagnosing HHV-6 meningitis, proper treatment protocols can be initiated earlier to reduce morbidity and mortality. Given the rarity of HHV-6 meningitis in immunocompetent adults, there are no established standard treatment guidelines; previous reported cases, as well as this case, suggest that either intravenous ganciclovir or intravenous foscarnet are the most reasonable first-line treatment options.

Indexed as

HHV-6infectious diseasemeningitispolymerase chain reactionviral meningitis

Identifiers

PMID32313475
PMCPMC7155960
OpenAlexW3004200973

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.