ArticleScientific reports2020
Bighorn sheep gut microbiomes associate with genetic and spatial structure across a metapopulation.
Article in Scientific reports, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
30 citing papers in PubMed.
- Article
- Dietary supplementation with fermented compound Chinese herbal medicine reshapes the gastrointestinal microbiota and enhances growth in suckling lambs.Microbiology spectrum · 2026Article
- Beyond distance-decay: The Mississippi River shapes gut microbiome communities in thebioRxiv : the preprint server for biology · 2026Article
- MHC class II genes influence the gut microbiota of wild golden snub-nosed monkeys.BMC microbiology · 2026Article
- The golden jackal (Canis aureus): interaction of fur and fecal microbiota, host genetics and animal traits.Animal microbiome · 2025Article
- Host and Microbe Scale Processes Shape Spatial Variation inbioRxiv : the preprint server for biology · 2025Article
- Nitrogen Utilization and Ruminal Microbiota of Hu Lambs in Response to Varying Dietary Metabolizable Protein Levels.Animals : an open access journal from MDPI · 2025Article
- Spatial variation of skin-associated microbiota in a green salamander metapopulation.Scientific reports · 2025Article
- The Effect ofAnimals : an open access journal from MDPI · 2025Article
- Interspecific variation in gut microbiome diversity across the Etosha National Park herbivore community.PloS one · 2025Article
- Article
- Dietary and environmental factors affecting the dynamics of the gut bacteria in Tibetan Awang sheep (Frontiers in microbiology · 2025Article
- Gut microbiome communities demonstrate fine-scale spatial variation in a closed, island bird population.ISME communications · 2025Article
- Enhancing Rumen Fermentation and Bacteria Community in Sika Deer (Animals : an open access journal from MDPI · 2024Article
- Comparison of average daily gain, apparent digestibility, rumen fermentation parameters and bacterial communities, and serum antioxidant indices in Leizhou goats fed with or without rumen-protected fat.Frontiers in veterinary science · 2024Article
- Specific gastrointestinal microbiota profiles in Chinese Tan sheep are associated with lauric acid content in muscle.BMC microbiology · 2023Article
- Fecal microbiota of the synanthropic golden jackal (Canis aureus).Animal microbiome · 2023Article
- Phylogenetically under-dispersed gut microbiomes are not correlated with host genomic heterozygosity in a genetically diverse reptile community.Molecular ecology · 2023Article
- Best practice for wildlife gut microbiome research: A comprehensive review of methodology for 16S rRNA gene investigations.Frontiers in microbiology · 2023Review
- Immunogenetic variation shapes the gut microbiome in a natural vertebrate population.Microbiome · 2022Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Studies in laboratory animals demonstrate important relationships between environment, host traits, and microbiome composition. However, host-microbiome relationships in natural systems are understudied. Here, we investigate metapopulation-scale microbiome variation in a wild mammalian host, the desert bighorn sheep (Ovis canadensis nelsoni). We sought to identify over-represented microbial clades and understand how landscape variables and host traits influence microbiome composition across the host metapopulation. To address these questions, we performed 16S sequencing on fecal DNA samples from thirty-nine bighorn sheep across seven loosely connected populations in the Mojave Desert and assessed relationships between microbiome composition, environmental variation, geographic distribution, and microsatellite-derived host population structure and heterozygosity. We first used a phylogenetically-informed algorithm to identify bacterial clades conserved across the metapopulation. Members of genus Ruminococcaceae, genus Lachnospiraceae, and family Christensenellaceae R7 group were among the clades over-represented across the metapopulation, consistent with their known roles as rumen symbionts in domestic livestock. Additionally, compositional variation among hosts correlated with individual-level geographic and genetic structure, and with population-level differences in genetic heterozygosity. This study identifies microbiome community variation across a mammalian metapopulation, potentially associated with genetic and geographic population structure. Our results imply that microbiome composition may diverge in accordance with landscape-scale environmental and host population characteristics.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.