Evidence map›Paper›PMID 32313106›Full record

ArticleScientific reports2020

Effect of excessive gestational weight on daughters' breast density at the end of puberty onset.

Ana López, María Luisa Garmendia, John Shepherd, Karin Michels, Camila Corvalán, Ana Pereira

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.3field-weighted citation impact, top 44% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 3 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 3 countries.

Ana LópezMaster in Nutrition Program, Institute of Nutrition and Food Technology, University of Chile, Santiago, Chile.
María Luisa GarmendiaInstitute of Nutrition and Food Technology, University of Chile, Santiago, Chile.
John ShepherdPopulation Sciences in the Pacific Program, University of Hawaii Cancer Center, Honolulu, Hawaii, USA.
Karin MichelsDepartment of Epidemiology, Fielding School of Public Health, University of California, Los Angeles, California, USA.
Camila CorvalánInstitute of Nutrition and Food Technology, University of Chile, Santiago, Chile.
Ana PereiraInstitute of Nutrition and Food Technology, University of Chile, Santiago, Chile. apereira@inta.uchile.cl.
University of Chile · CLUniversity of Freiburg · DEUniversity of Hawaii Cancer Center

Funding

Predictors of Mammary Gland Development & Breast Fibroglandular Volume at pubertyR01CA158313 · NCI · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI MICHELS, KARIN B · 2012 to 2015
$1.9M
NCI NIH HHS R01 CA158313
6 · The paper itself

Abstract

The effect of excessive gestational weight gain (EGWG) is related to adverse health outcomes in the offspring; however, its effect on the daughters' breast density is unclear. We aimed to assess the association between EGWG and daughters' breast composition (% of fibroglandular volume (%FGV) and absolute fibroglandular volume (AFGV)) at Tanner stage 4 (Tanner B4)). We included 341 girls and their mothers from an ongoing cohort of low-income Chilean girls born from 2002-2003. Maternal gestational weight gain was self-reported in 2007, and breast density by digital mammography was measured in 2010. Weight, height and breast composition by dual X-ray absorptiometry (DXA) were measured in daughters at Tanner B4. Logistic regression models were run to assess the association between EGWG and the 80th percentile of %FGV and AFGV. Mean gestational weight gain was 13.7 kg (SD = 6.9 kg). Women with pregestational overweight or obesity exceeded the recommended gestational weight gain (58.8% vs. 31.8%, respectively). Daughters of women who had EGWG had higher levels of AFGV (OR: 2.02; 95%CI 1.16-3.53) at Tanner B4, which could be explained by metabolic and hormonal exposure in utero. However, we did not observe an association with %FGV.

Indexed as

Gestational Weight GainAbsorptiometry, PhotonAdolescentAdultBreast DensityChildChileFemaleHumansInheritance PatternsLogistic ModelsLongitudinal StudiesMammary Glands, HumanMammographyMothersNuclear Family

Identifiers

PMID32313106
PMCPMC7171116
OpenAlexW3016781889

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.