Evidence map›Paper›PMID 32313079›Full record

ArticleScientific reports2020

Limits in the detection of m

Alexa B R McIntyre, Nandan S Gokhale, Leandro Cerchietti, Samie R Jaffrey, Stacy M Horner, Christopher E Mason

Abstract read
In one paragraph

Article in Scientific reports, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 162 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
162citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

162 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. RNA methylation in vascular disease: a systematic review.Journal of cardiothoracic surgery · 2022
    Pooled it
  2. Review
  3. Article
  4. Review
  5. Review
  6. Review
  7. Review
  8. NPoultry science · 2026
    Review
  9. Article
  10. Review
  11. mMolecular medicine reports · 2026
    Review
  12. Review
  13. Review
  14. Review
  15. Article
  16. Prolonged Sample Storage Reshapes the mInternational journal of molecular sciences · 2026
    Article
  17. Article
  18. The bladder cancer mEMBO reports · 2026
    Article
  19. m6A epigenetic modification of viral RNA is critical for the transmission cycle of mosquito-borne flaviviruses.Proceedings of the National Academy of Sciences of the United States of America · 2026
    Article
  20. Two codes of RNA editing by deamination in human diseases.Experimental & molecular medicine · 2026
    Review

102 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Alexa B R McIntyreDepartment of Physiology and Biophysics, Weill Cornell Medicine, New York City, NY, 10065, USA. abm237@cornell.edu.
Nandan S GokhaleDepartment of Molecular Genetics and Microbiology, Duke University Medical Center, Durham, NC, 27710, USA.
Leandro CerchiettiDivision of Hematology and Medical Oncology, Weill Cornell Medicine, New York City, NY, 10065, USA.
Samie R JaffreyDepartment of Pharmacology, Weill Cornell Medicine, New York City, NY, 10065, USA.
Stacy M HornerDepartment of Molecular Genetics and Microbiology, Duke University Medical Center, Durham, NC, 27710, USA. stacy.horner@duke.edu.
Christopher E MasonDepartment of Physiology and Biophysics, Weill Cornell Medicine, New York City, NY, 10065, USA. chm2042@med.cornell.edu.

Funding

New mechanisms and technologies for understanding post-transcriptional gene regulation in neuronsR35NS111631 · NINDS · WEILL MEDICAL COLL OF CORNELL UNIV · PI SAMIE R JAFFREY · 2019 to 2026
$8.6M
Defining the role of the RNA modification N6-methyladenosine in the hepatitis C virus lifecycleR01AI125416 · NIAID · DUKE UNIVERSITY · PI Stacy Michelle Horner · 2016 to 2026
$5.5M
The Spatiotemporal Landscape of the Human Brain EpitranscriptomeR01MH117406 · NIMH · WEILL MEDICAL COLL OF CORNELL UNIV · PI MASON, CHRISTOPHER EDWARD · 2018 to 2022
$3.3M
Mapping the RNA modification N6-methyladenosine during Zika virus infectionR21AI129851 · NIAID · WEILL MEDICAL COLL OF CORNELL UNIV · PI HORNER, STACY MICHELLE, MASON, CHRISTOPHER EDWARD · 2017 to 2018
$469k
NIAID NIH HHS R01 AI125416NIAID NIH HHS R21 AI129851NIMH NIH HHS R01 MH117406NINDS NIH HHS R35 NS111631
6 · The paper itself

Abstract

Many cellular mRNAs contain the modified base m

Indexed as

AdenosineAlgorithmsBase SequenceHumansImmunoprecipitationMethylationRNARNA, MessengerSequence Analysis, RNASoftwareAdenosineRNARNA, Messenger

Identifiers

PMID32313079
PMCPMC7170965

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.