Evidence map›Paper›PMID 32313029›Full record

ArticleNature communications2020

Quantitative cellular-resolution map of the oxytocin receptor in postnatally developing mouse brains.

Kyra T Newmaster, Zachary T Nolan, Uree Chon, Daniel J Vanselow, Abigael R Weit, Manal Tabbaa, Shizu Hidema, Katsuhiko Nishimori, Elizabeth A D Hammock, Yongsoo Kim

Open access · goldAbstract read
In one paragraph

Article in Nature communications, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 74 papers.

0numbers the graph read from it
0cells of the map it votes in
74citing papers in PubMed
13.2field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

74 citing papers in PubMed, 106 citations in OpenAlex.

  1. Lasting effects of early-life oxytocin treatment on LTP and episodic memory in a mouse model of Fragile X syndrome.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2026
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14 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 2 countries.

Kyra T NewmasterDepartment of Neural and Behavioral Sciences, Penn State University, Hershey, PA, USA.ORCID http://orcid.org/0000-0002-5544-1220
Zachary T NolanDepartment of Neural and Behavioral Sciences, Penn State University, Hershey, PA, USA.ORCID http://orcid.org/0000-0003-3064-2058
Uree ChonDepartment of Neural and Behavioral Sciences, Penn State University, Hershey, PA, USA.ORCID http://orcid.org/0000-0002-5620-5430
Daniel J VanselowDepartment of Neural and Behavioral Sciences, Penn State University, Hershey, PA, USA.ORCID http://orcid.org/0000-0002-9221-8634
Abigael R WeitDepartment of Neural and Behavioral Sciences, Penn State University, Hershey, PA, USA.ORCID http://orcid.org/0000-0002-5463-5752
Manal TabbaaDepartment of Psychology and Program in Neuroscience, Florida State University, Tallahassee, FL, USA.
Shizu HidemaTohoku University Graduate School of Agricultural Science, Miyagi, Japan.
Katsuhiko NishimoriTohoku University Graduate School of Agricultural Science, Miyagi, Japan.
Elizabeth A D HammockDepartment of Psychology and Program in Neuroscience, Florida State University, Tallahassee, FL, USA.ORCID http://orcid.org/0000-0001-7668-745X
Yongsoo KimDepartment of Neural and Behavioral Sciences, Penn State University, Hershey, PA, USA. yuk17@psu.edu.ORCID http://orcid.org/0000-0002-4277-0279
Pennsylvania State University · USFlorida State University · USFukushima Medical University · JP

Funding

Groundwork for a Synchrotron MicroCT Imaging Resource for Biology (SMIRB)R24OD018559 · OD · PENNSYLVANIA STATE UNIV HERSHEY MED CTR · PI CHENG, KEITH CHI · 2015 to 2022
$6.4M
Chemosensory Training Program (CTP)T32DC000044 · NIDCD · FLORIDA STATE UNIVERSITY · PI DEBRA Ann FADOOL · 1995 to 2026
$5.3M
Brain-wide input and output wiring diagram of oxytocin neurons and its function in claustrum-endopiriform complexR01MH116176 · NIMH · PENNSYLVANIA STATE UNIV HERSHEY MED CTR · PI KIM, YONGSOO · 2018 to 2022
$2.4M
Neural mechanisms of infant attachmentR01MH114994 · NIMH · FLORIDA STATE UNIVERSITY · PI HAMMOCK, ELIZABETH A.D. · 2018 to 2022
$1.9M
NIDCD NIH HHS T32 DC000044NIH HHS R24 OD018559NIMH NIH HHS R01 MH114994NIMH NIH HHS R01 MH116176
6 · The paper itself

Abstract

The oxytocin receptor (OTR) plays critical roles in social behavior development. Despite its significance, brain-wide quantitative understanding of OTR expression remains limited in postnatally developing brains. Here, we develop postnatal 3D template brains to register whole brain images with cellular resolution to systematically quantify OTR cell densities. We utilize fluorescent reporter mice (Otr

Indexed as

AnimalsBrainBrain MappingDown-RegulationFemaleGene Expression Regulation, DevelopmentalHypothalamusMaleMiceMice, KnockoutMice, TransgenicNervous SystemNeuronsOxytocinReceptors, OxytocinSex CharacteristicsOxytocinReceptors, Oxytocin

Identifiers

PMID32313029
PMCPMC7171089
OpenAlexW3016718510

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.