Evidence map›Paper›PMID 32312942›Full record

Observational studyAging2020

Dynamics of outcome after aneurysmal subarachnoid hemorrhage.

Alexander Hammer, Gholamreza Ranaie, Eduard Yakubov, Frank Erbguth, Markus Holtmannspoetter, Hans-Herbert Steiner, Hendrik Janssen

Abstract readObservational Study
In one paragraph

Observational study in Aging, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. A visualized MAC nomogram online predicts the risk of three-month mortality in Chinese elderly aneurysmal subarachnoid hemorrhage patients undergoing endovascular coiling.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2023
    Article
  9. Observational
  10. Article
  11. Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Alexander HammerDepartment of Neurosurgery, Paracelsus Medical University, Nuremberg 90471, Bavaria, Germany.
Gholamreza RanaieDepartment of Neurosurgery, Paracelsus Medical University, Nuremberg 90471, Bavaria, Germany.
Eduard YakubovDepartment of Neurosurgery, Paracelsus Medical University, Nuremberg 90471, Bavaria, Germany.
Frank ErbguthDepartment of Neurology, Paracelsus Medical University, Nuremberg 90471, Bavaria, Germany.
Markus HoltmannspoetterDepartment of Neuroradiology, Nuremberg General Hospital, Nuremberg 90471, Bavaria, Germany.
Hans-Herbert SteinerDepartment of Neurosurgery, Paracelsus Medical University, Nuremberg 90471, Bavaria, Germany.
Hendrik JanssenDepartment of Neuroradiology, Ingolstadt General Hospital, Ingolstadt 85049, Bavaria, Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In this observational study, we analyzed and described the dynamics of the outcome after aneurysmal subarachnoid hemorrhage (SAH) in a collective of 203 cases. We detected a significant improvement of the mean aggregate modified Rankin Score (mRS) in every time interval from discharge to 6 months and up to 1 year. Every forth to fifth patient with potential of recovery (mRS 1-5) at discharge improved by 1 mRS point in the time interval from 6 month to 1 year (22.6%). Patients with mRS 3 at discharge had a remarkable late recovery rate (73.3%, p = 0.000085). Multivariate analysis revealed age ≤ 65 years (odds ratio 4.93; p = 0.0045) and "World Federation of Neurological Surgeons" (WFNS) grades I and II (odds ratio 4.77; p = 0.0077) as significant predictors of early improvement (discharge to 6 months). Absence of a shunting procedure (odds ratio 8.32; p = 0.0049) was a significant predictor of late improvement (6 months to 1 year), but not age ≤ 65 years (p = 0.54) and WFNS grades I and II (p = 0.92). Thus, late recovery (6 month to 1 year) is significant and independent from age and WFNS grade.

Indexed as

AdultAgedAge FactorsFemaleHumansIntracranial AneurysmMaleMiddle AgedMultivariate AnalysisSubarachnoid HemorrhageTime Factorsagingintracranial aneurysmoutcomestrokesubarachnoid hemorrhage

Identifiers

PMID32312942
PMCPMC7202490

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.