Evidence map›Paper›PMID 32312886›Full record

ArticleThe Journal of neuroscience : the official journal of the Society for Neuroscience2020

Synchronous Infra-Slow Oscillations Organize Ensembles of Accessory Olfactory Bulb Projection Neurons into Distinct Microcircuits.

Chryssanthi Tsitoura, Sebastian T Malinowski, Julia Mohrhardt, Rudolf Degen, Brett T DiBenedictis, Yuan Gao, Katja Watznauer, Kira Gerhold, Maximilian Nagel, Monika Weber and 5 more

Open access · bronzeAbstract read
In one paragraph

Article in The Journal of neuroscience : the official journal of the Society for Neuroscience, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.5field-weighted citation impact, top 40% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 9 citations in OpenAlex.

  1. Article
  2. Presynaptic GABAFrontiers in cellular neuroscience · 2023
    Article
  3. Article
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 4 institutions in 3 countries.

Chryssanthi TsitouraDepartment of Chemosensation, Institute for Biology II, RWTH Aachen University, Aachen, D-52074, Germany.ORCID 0000-0002-9856-0043
Sebastian T MalinowskiDepartment of Chemosensation, Institute for Biology II, RWTH Aachen University, Aachen, D-52074, Germany.ORCID 0000-0001-7877-5971
Julia MohrhardtDepartment of Chemosensation, Institute for Biology II, RWTH Aachen University, Aachen, D-52074, Germany.ORCID 0000-0002-1939-7920
Rudolf DegenDepartment of Chemosensation, Institute for Biology II, RWTH Aachen University, Aachen, D-52074, Germany.ORCID 0000-0002-8513-9030
Brett T DiBenedictisDepartment of Biology, Boston University, Boston, Massachusetts 02115.
Yuan GaoDepartment of Biology, Boston University, Boston, Massachusetts 02115.
Katja WatznauerDepartment of Chemosensation, Institute for Biology II, RWTH Aachen University, Aachen, D-52074, Germany.
Kira GerholdDepartment of Chemosensation, Institute for Biology II, RWTH Aachen University, Aachen, D-52074, Germany.
Maximilian NagelDepartment of Chemosensation, Institute for Biology II, RWTH Aachen University, Aachen, D-52074, Germany.
Monika WeberDepartment of Chemosensation, Institute for Biology II, RWTH Aachen University, Aachen, D-52074, Germany.
Markus RothermelResearch Training Group 2416 MultiSenses-MultiScales, RWTH Aachen University, Aachen, D-52074, Germany.ORCID 0000-0002-0929-993X
Ileana L Hanganu-OpatzDevelopmental Neurophysiology, Center for Molecular Neurobiology, University Medical Center Hamburg-Eppendorf, Hamburg, D-20251, Germany.
Yoram Ben-ShaulFaculty of Medicine, Department of Medical Neurobiology, The Hebrew University of Jerusalem, Jerusalem 91120, Israel.ORCID 0000-0002-0407-4221
Ian G DavisonDepartment of Biology, Boston University, Boston, Massachusetts 02115.
Marc SpehrDepartment of Chemosensation, Institute for Biology II, RWTH Aachen University, Aachen, D-52074, Germany m.spehr@sensorik.rwth-aachen.de.ORCID 0000-0001-6616-4196
RWTH Aachen University · DEBoston University · USHebrew University of Jerusalem · ILUniversität Hamburg · DE

Funding

Neural circuits for regulating social behavior in rodentsR01DC017234 · NIDCD · BOSTON UNIVERSITY (CHARLES RIVER CAMPUS) · PI DAVISON, IAN GORDON · 2019 to 2023
$1.5M
NIDCD NIH HHS R01 DC017234
6 · The paper itself

Abstract

The accessory olfactory system controls social and sexual behavior. In the mouse accessory olfactory bulb, the first central stage of information processing along the accessory olfactory pathway, projection neurons (mitral cells) display infra-slow oscillatory discharge with remarkable periodicity. The physiological mechanisms that underlie this default output state, however, remain controversial. Moreover, whether such rhythmic infra-slow activity patterns exist in awake behaving mice and whether such activity reflects the functional organization of the accessory olfactory bulb circuitry remain unclear. Here, we hypothesize that mitral cell ensembles form synchronized microcircuits that subdivide the accessory olfactory bulb into segregated functional clusters. We use a miniature microscope to image the Ca

Indexed as

Action PotentialsAnimalsMiceNerve NetNeuronsOlfactory BulbOlfactory Pathwaysaccessory olfactory bulbchemosensory codingensemble formationmitral cellsneural oscillationsvomeronasal system

Identifiers

PMID32312886
PMCPMC7244196
OpenAlexW3016675237

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.