Evidence map›Paper›PMID 32312824›Full record

ArticleCMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne2020

Five-year risk of admission to long-term care home and death for older adults given a new diagnosis of dementia: a population-based retrospective cohort study.

Gregory Huyer, Catherine R L Brown, Sarah Spruin, Amy T Hsu, Stacey Fisher, Douglas G Manuel, Susan E Bronskill, Danial Qureshi, Peter Tanuseputro

Erratum issuedOpen access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 17 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed, 1 pooled it
2.9field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 1 synthesis or guideline pooled it, 42 citations in OpenAlex.

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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 1 country.

Gregory HuyerClinical Epidemiology Program (Huyer, Brown, Hsu, Fisher, Manuel, Qureshi, Tanuseputro), Ottawa Hospital Research Institute; Telfer School of Management (Huyer) and School of Epidemiology and Public Health (Brown, Fisher, Tanuseputro), University of Ottawa; Bruyere Research Institute (Hsu, Qureshi, Tanuseputro); ICES uOttawa (Spruin, Hsu, Manuel, Tanuseputro), Ottawa, Ont.; ICES Central (Bronskill); Institute of Health Policy, Management and Evaluation (Bronskill), Dalla Lana School of Public Health, University of Toronto, Toronto, Ont.
Catherine R L BrownClinical Epidemiology Program (Huyer, Brown, Hsu, Fisher, Manuel, Qureshi, Tanuseputro), Ottawa Hospital Research Institute; Telfer School of Management (Huyer) and School of Epidemiology and Public Health (Brown, Fisher, Tanuseputro), University of Ottawa; Bruyere Research Institute (Hsu, Qureshi, Tanuseputro); ICES uOttawa (Spruin, Hsu, Manuel, Tanuseputro), Ottawa, Ont.; ICES Central (Bronskill); Institute of Health Policy, Management and Evaluation (Bronskill), Dalla Lana School of Public Health, University of Toronto, Toronto, Ont.
Sarah SpruinClinical Epidemiology Program (Huyer, Brown, Hsu, Fisher, Manuel, Qureshi, Tanuseputro), Ottawa Hospital Research Institute; Telfer School of Management (Huyer) and School of Epidemiology and Public Health (Brown, Fisher, Tanuseputro), University of Ottawa; Bruyere Research Institute (Hsu, Qureshi, Tanuseputro); ICES uOttawa (Spruin, Hsu, Manuel, Tanuseputro), Ottawa, Ont.; ICES Central (Bronskill); Institute of Health Policy, Management and Evaluation (Bronskill), Dalla Lana School of Public Health, University of Toronto, Toronto, Ont.
Amy T HsuClinical Epidemiology Program (Huyer, Brown, Hsu, Fisher, Manuel, Qureshi, Tanuseputro), Ottawa Hospital Research Institute; Telfer School of Management (Huyer) and School of Epidemiology and Public Health (Brown, Fisher, Tanuseputro), University of Ottawa; Bruyere Research Institute (Hsu, Qureshi, Tanuseputro); ICES uOttawa (Spruin, Hsu, Manuel, Tanuseputro), Ottawa, Ont.; ICES Central (Bronskill); Institute of Health Policy, Management and Evaluation (Bronskill), Dalla Lana School of Public Health, University of Toronto, Toronto, Ont.
Stacey FisherClinical Epidemiology Program (Huyer, Brown, Hsu, Fisher, Manuel, Qureshi, Tanuseputro), Ottawa Hospital Research Institute; Telfer School of Management (Huyer) and School of Epidemiology and Public Health (Brown, Fisher, Tanuseputro), University of Ottawa; Bruyere Research Institute (Hsu, Qureshi, Tanuseputro); ICES uOttawa (Spruin, Hsu, Manuel, Tanuseputro), Ottawa, Ont.; ICES Central (Bronskill); Institute of Health Policy, Management and Evaluation (Bronskill), Dalla Lana School of Public Health, University of Toronto, Toronto, Ont.
Douglas G ManuelClinical Epidemiology Program (Huyer, Brown, Hsu, Fisher, Manuel, Qureshi, Tanuseputro), Ottawa Hospital Research Institute; Telfer School of Management (Huyer) and School of Epidemiology and Public Health (Brown, Fisher, Tanuseputro), University of Ottawa; Bruyere Research Institute (Hsu, Qureshi, Tanuseputro); ICES uOttawa (Spruin, Hsu, Manuel, Tanuseputro), Ottawa, Ont.; ICES Central (Bronskill); Institute of Health Policy, Management and Evaluation (Bronskill), Dalla Lana School of Public Health, University of Toronto, Toronto, Ont.
Susan E BronskillClinical Epidemiology Program (Huyer, Brown, Hsu, Fisher, Manuel, Qureshi, Tanuseputro), Ottawa Hospital Research Institute; Telfer School of Management (Huyer) and School of Epidemiology and Public Health (Brown, Fisher, Tanuseputro), University of Ottawa; Bruyere Research Institute (Hsu, Qureshi, Tanuseputro); ICES uOttawa (Spruin, Hsu, Manuel, Tanuseputro), Ottawa, Ont.; ICES Central (Bronskill); Institute of Health Policy, Management and Evaluation (Bronskill), Dalla Lana School of Public Health, University of Toronto, Toronto, Ont.
Danial QureshiClinical Epidemiology Program (Huyer, Brown, Hsu, Fisher, Manuel, Qureshi, Tanuseputro), Ottawa Hospital Research Institute; Telfer School of Management (Huyer) and School of Epidemiology and Public Health (Brown, Fisher, Tanuseputro), University of Ottawa; Bruyere Research Institute (Hsu, Qureshi, Tanuseputro); ICES uOttawa (Spruin, Hsu, Manuel, Tanuseputro), Ottawa, Ont.; ICES Central (Bronskill); Institute of Health Policy, Management and Evaluation (Bronskill), Dalla Lana School of Public Health, University of Toronto, Toronto, Ont.
Peter TanuseputroClinical Epidemiology Program (Huyer, Brown, Hsu, Fisher, Manuel, Qureshi, Tanuseputro), Ottawa Hospital Research Institute; Telfer School of Management (Huyer) and School of Epidemiology and Public Health (Brown, Fisher, Tanuseputro), University of Ottawa; Bruyere Research Institute (Hsu, Qureshi, Tanuseputro); ICES uOttawa (Spruin, Hsu, Manuel, Tanuseputro), Ottawa, Ont.; ICES Central (Bronskill); Institute of Health Policy, Management and Evaluation (Bronskill), Dalla Lana School of Public Health, University of Toronto, Toronto, Ont. ptanuseputro@ohri.ca.
Bruyère · CAOttawa Hospital · CAOttawa Hospital Research InstituteUniversity of Ottawa · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundAfter diagnosis of a health condition, information about survival and potential transition from community into institutional care can be helpful for patients and care providers. We sought to describe the association between a new diagnosis of dementia and risk of admission to a long-term care home and death at 5 years.

methodsWe conducted a population-based retrospective cohort study using linked health administrative databases. We identified individuals aged 65 years or older, living in the community, with a first documented diagnosis of dementia between Jan. 1, 2010, and Dec. 31, 2012, in Ontario, Canada. Dementia diagnosis was captured using diagnostic codes from hospital discharges, physician billings, assessments conducted for home care and long-term care, and dispensed prescriptions for cholinesterase inhibitors. Our primary outcome measures were 5-year risk of death and placement in a long-term care home, adjusted for sociodemographic and clinical factors.

resultsWe identified 108 757 individuals in our study cohort. By the end of 5 years, 24.4% remained alive in the community and 20.5% were living in a long-term care home. Of the 55.1% who died, about half (27.9%) were admitted to a long-term care home before death. Three risk factors were associated with increased odds of death: older age (age ≥ 90 yr; odds ratio [OR] 9.5, 95% confidence interval [CI] 8.8-10.2 [reference: age 65-69 yr]), male sex (OR 1.7, 95% CI 1.6-1.7), and the presence of organ failure, including chronic obstructive pulmonary disease (OR 1.7, 95% CI 1.7-1.8), congestive heart failure (OR 2.0, 95% CI 1.9-2.0) and renal failure (OR 1.7, 95% CI 1.6-1.8). Groups formed by combinations of these 3 factors had an observed 5-year risk of death varying between 22% and 91%.

interpretationAmong community-dwelling older adults with newly identified dementia in Ontario, the majority died or were admitted to a long-term care home within 5 years. This information may be helpful for discussions on prognosis and need for admission to long-term care.

Indexed as

Long-Term CarePatient AdmissionAgedAged, 80 and overCohort StudiesDatabases, FactualDementiaFemaleHealth Services for the AgedHumansMaleOntarioRetrospective StudiesSurvival Analysis

Identifiers

PMID32312824
PMCPMC7207184
OpenAlexW3016692789

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.