Evidence map›Paper›PMID 32312642›Full record

ReviewUrologic oncology2020

Impact of body size and body composition on bladder cancer outcomes: Risk stratification and opportunity for novel interventions.

Alejandro Sanchez, Suzanne Kissel, Adriana Coletta, Jessica Scott, Helena Furberg

Abstract readReview
In one paragraph

Review in Urologic oncology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed, 3 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 3 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Testosterone replacement therapy and bladder cancer.Canadian Urological Association journal = Journal de l'Association des urologues du Canada · 2025
    Review
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Associations between body mass index and bladder cancer survival: Is the obesity paradox short-lived?Canadian Urological Association journal = Journal de l'Association des urologues du Canada · 2022
    Article
  12. Sarcopenia as an independent predictor for venous thromboembolism events in bladder cancer patients undergoing radical cystectomy.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2022
    Article
  13. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Alejandro SanchezDivision of Urology, Huntsman Cancer Institute, University of Utah, Salt Lake City, UT.
Suzanne KisselCancer Control and Population Sciences Program, Huntsman Cancer Institute, Salt Lake City, UT.
Adriana ColettaCancer Control and Population Sciences Program, Huntsman Cancer Institute, Salt Lake City, UT; Department of Health, Kinesiology, and Recreation, The University of Utah, Salt Lake City, UT.
Jessica ScottDepartment of Epidemiology and Biostatistics, Memorial Sloan Kettering Cancer Center, New York, NY.
Helena FurbergDepartment of Epidemiology and Biostatistics, Memorial Sloan Kettering Cancer Center, New York, NY. Electronic address: Furberga@mskcc.org.

Funding

X-RAY CRYSTALLOGRAPHYP30CA008748 · NCI · SLOAN-KETTERING INSTITUTE FOR CANCER RES · PI Hongbiao Carl Lekaye · 1985 to 2026
$347.4M
Body composition and the obesity paradox in clear cell renal cell carcinomaR01CA233885 · NCI · SLOAN-KETTERING INST CAN RESEARCH · PI FURBERG-BARNES, ANNA HELENA · 2019 to 2023
$3.3M
NCI NIH HHS P30 CA008748NCI NIH HHS R01 CA233885
6 · The paper itself

Abstract

Body size is emerging as a novel and clinically-relevant patient factor in bladder cancer research. Historically, a patient's body mass index (BMI) has been used as a proxy for obesity but it shows inconsistent associations with risk of developing the disease as well as with most clinical outcomes. More specific body composition features can be derived for patients using a variety of methods. To date, skeletal muscle measurements derived from preoperative computed tomography scans have shown the most consistent associations with clinical outcomes. Importantly, skeletal muscle can potentially be modified through resistance training and/or nutritional interventions. Large scale studies that evaluate the prognostic impact of not only body composition features at baseline but also describe changes in body composition post-treatment are needed to move the field forward to ultimately improve clinical outcomes for bladder cancer patients.

Indexed as

Body CompositionBody SizeRisk AssessmentHumansTreatment OutcomeUrinary Bladder NeoplasmsAdiposityBladder cancerBody compositionBody mass indexExerciseObesitySarcopeniaSkeletal muscle

Identifiers

PMID32312642
PMCPMC8245008

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.