Evidence map›Paper›PMID 32312347›Full record

ArticlePublic health nutrition2021

Association between dietary sodium intake and non-alcoholic fatty liver disease in the US population.

Long Zhou, Yuxuan Yang, Yang Feng, Xiaodan Zhao, Yameng Fan, Jie Rong, Liancheng Zhao, Yan Yu

Open access · greenAbstract read
In one paragraph

Article in Public health nutrition, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
2.8field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 34 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Long Zhou *Department of Nutrition and Food Safety, School of Public Health, Xi'an Jiaotong University Health Science Center, Xi'an710061, China.
Yuxuan Yang *Department of Stomatology, Xi'an Jiaotong University Health Science Center, Xi'an710061, China.
Yang FengDepartment of Nutrition and Food Safety, School of Public Health, Xi'an Jiaotong University Health Science Center, Xi'an710061, China.
Xiaodan ZhaoDepartment of Stomatology, Xi'an Jiaotong University Health Science Center, Xi'an710061, China.
Yameng FanDepartment of Nutrition and Food Safety, School of Public Health, Xi'an Jiaotong University Health Science Center, Xi'an710061, China.
Jie RongDepartment of Nutrition and Food Safety, School of Public Health, Xi'an Jiaotong University Health Science Center, Xi'an710061, China.
Liancheng ZhaoDivision of Prevention and Community Health, National Center for Cardiovascular Disease, Fuwai Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing100037, China.
Yan YuDepartment of Nutrition and Food Safety, School of Public Health, Xi'an Jiaotong University Health Science Center, Xi'an710061, China.
Xi'an Jiaotong University · CNChinese Academy of Medical Sciences & Peking Union Medical College · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo explore the association between dietary Na intake and non-alcoholic fatty liver disease (NAFLD) in a nationally representative sample of the US population.

designIn this cross-sectional study, the associations between Na intake and NAFLD, defined by the hepatic steatosis index (HSI) and the fatty liver index (FLI), were assessed through multivariable logistic regression models.

settingCommunities in the USA from 2007 to 2014.

participantsMen and women aged 20 years and older.

resultsA total of 11 022 participants were included in the HSI-defined NAFLD analysis, and a subsample of 5320 participants was included in the FLI-defined NAFLD analysis. Compared with the lowest quartile of Na intake, the highest quartile had a multivariate-adjusted OR and 95 % CI of 1·46 (1·29, 1·65) for NAFLD as defined by HSI, and 1·41 (1·18, 1·69) for NAFLD as defined by FLI. This association was, to some degree, attenuated but remained significant after adjusting for several related metabolic parameters, including BMI, hypertension, hypercholesterolaemia, and diabetes.

conclusionsFindings from the current study indicate that dietary Na intake is positively associated with NAFLD in US adults.

Indexed as

Non-alcoholic Fatty Liver DiseaseSodium, DietaryAdultCross-Sectional StudiesFemaleHumansMaleNutritional StatusSodiumSodiumSodium, DietaryCross-sectional studyNa intakeNon-alcoholic fatty liver diseaseSalt intake

Identifiers

PMID32312347
PMCPMC10195540
OpenAlexW3016704197

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.