Evidence map›Paper›PMID 32312265›Full record

Trial reportBMC musculoskeletal disorders2020

Exercise program combined with electrophysical modalities in subjects with knee osteoarthritis: a randomised, placebo-controlled clinical trial.

Cid André Fidelis de Paula Gomes, Fabiano Politti, Cheila de Souza Bacelar Pereira, Aron Charles Barbosa da Silva, Almir Vieira Dibai-Filho, Adriano Rodrigues de Oliveira, Daniela Aparecida Biasotto-Gonzalez

3 registry-linked trialsOpen access · goldAbstract readRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in BMC musculoskeletal disorders, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 3 registered trials, which are not on this map. Cited by 14 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed, 2 pooled it
2.8field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT02636764 nacompletednot on this map

Influence of Using Physical Therapy Resources for Knee Osteoarthritis

TypeinterventionalSponsorUniversity of Nove de JulhoRan2016 to 2018Enrolled100ConditionsOsteoarthritis, Physical Therapy ModalitiesArmsexercise, interferential current, short-wave diathermy, Low level laser therapy, Ultrasound therapy
NCT05975957 naunknown statusnot on this mapstarted 2023, after this paper: background citation

Photobiomodulation Therapy to Reduce Pain and Inflammation in Patients With Gonarthrosis: a Multicenter Randomized, Double-blind, Placebo-controlled Clinical Trial

TypeinterventionalSponsorD'Or Institute for Research and EducationRan2023 to 2025Enrolled238ConditionsOsteoarthritis, GonarthrosisArmsPhotomodulation Therapy with the Light-Aid system, Control
NCT06289218 nanot yet recruitingnot on this mapstarted 2025, after this paper: background citation

Kinesio Taping Versus Interferential Current Therapy in Treating Knee Osteoarthritis: a Comparative Study

TypeinterventionalSponsorCairo UniversityRan2025 to 2025Enrolled63ConditionsKnee OsteoarthritisArmsinterferential current, kinesio taping, exercise
3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 2 syntheses or guidelines pooled it, 30 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Cid André Fidelis de Paula GomesPostgraduate Program in Rehabilitation Sciences, Nove de Julho University, Rua Vergueiro, 235/249, 2° Subsolo, Liberdade, São Paulo, SP, CEP 01504-001, Brazil.ORCID https://orcid.org/0000-0001-6627-7537
Fabiano PolittiPostgraduate Program in Rehabilitation Sciences, Nove de Julho University, Rua Vergueiro, 235/249, 2° Subsolo, Liberdade, São Paulo, SP, CEP 01504-001, Brazil.ORCID https://orcid.org/0000-0001-6383-0034
Cheila de Souza Bacelar PereiraPostgraduate Program in Rehabilitation Sciences, Nove de Julho University, Rua Vergueiro, 235/249, 2° Subsolo, Liberdade, São Paulo, SP, CEP 01504-001, Brazil.ORCID https://orcid.org/0000-0001-9031-5396
Aron Charles Barbosa da SilvaPostgraduate Program in Rehabilitation Sciences, Nove de Julho University, Rua Vergueiro, 235/249, 2° Subsolo, Liberdade, São Paulo, SP, CEP 01504-001, Brazil. charlesmam43@gmail.com.ORCID https://orcid.org/0000-0003-4281-2616
Almir Vieira Dibai-FilhoPostgraduate Program in Physical Education, Federal University of Maranhão, São Luís, MA, Brazil.ORCID https://orcid.org/0000-0001-5403-8248
Adriano Rodrigues de OliveiraPostgraduate Program in Rehabilitation Sciences, Nove de Julho University, Rua Vergueiro, 235/249, 2° Subsolo, Liberdade, São Paulo, SP, CEP 01504-001, Brazil.ORCID https://orcid.org/0000-0002-7848-7686
Daniela Aparecida Biasotto-GonzalezPostgraduate Program in Rehabilitation Sciences, Nove de Julho University, Rua Vergueiro, 235/249, 2° Subsolo, Liberdade, São Paulo, SP, CEP 01504-001, Brazil.ORCID https://orcid.org/0000-0002-8498-0557
Universidade Nove de Julho · BRUniversidade Federal do Maranhão · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundIt is not yet clear which of the various electrophysical modalities used in clinical practice is the one that contributes most positively when added to an exercise program in patients with knee osteoarthritis (OA). The aim of the present study was to analyze the clinical effects of the inclusion of interferential current therapy (ICT), shortwave diathermy therapy (SDT) and photobiomodulation (PHOTO) into an exercise program in patients with knee OA.

methodsThis prospective, five-arm, randomised, placebo-controlled trial was carried out with blinded participants and examiners. We recruited 100 volunteers aged 40 to 80 years with knee OA. Participants were allocated into five groups: exercise, exercise + placebo, exercise + ICT, exercise + SDT, and exercise + PHOTO. The outcome measures included Western Ontario and McMaster Universities (WOMAC), numerical rating pain scale (NRPS), pressure pain threshold (PPT), self-perceived fatigue and sit-to-stand test (STST), which were evaluated before and after 24 treatment sessions at a frequency of three sessions per week.

resultsIn all groups, there was a significant improvement (p < 0.05) in all variables over time, except pressure pain threshold. We observed significant differences (p < 0.05) between the groups for WOMAC function (exercise vs. exercise + placebo, mean difference [MD] = 5.55, 95% confidence interval [CI] = 3.63 to 7.46; exercise vs. exercise + ICT, MD = 3.40, 95% CI = 1.46 to 5.33; exercise vs. exercise + SDT, MD = 4.75, 95% CI = 1.85 to 7.64; exercise vs. exercise + PHOTO, MD = 5.45, 95% CI = 3.12 to 7.77) and WOMAC pain, with better scores achieved by the exercise group. However, these differences were not clinically relevant when considering the minimum clinically important difference.

conclusionThe addition of ICT, SDT or PHOTO into an exercise program for individuals with knee OA is not superior to exercise performed in isolation in terms of clinical benefit. clinicaltrials.gov: NCT02636764, registered on March 29, 2014.

Indexed as

AdultAgedAged, 80 and overCombined Modality TherapyElectric Stimulation TherapyExerciseExercise TherapyFemaleHumansLow-Level Light TherapyMaleMiddle AgedOsteoarthritis, KneePain ManagementPain ThresholdProspective StudiesExerciseKnee osteoarthritisKnee painModalitiesPhysical therapy

Identifiers

PMID32312265
PMCPMC7171730
OpenAlexW3016663891

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.