ArticleBMC bioinformatics2020
DeSignate: detecting signature characters in gene sequence alignments for taxon diagnoses.
Article in BMC bioinformatics, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
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Who cites it
10 citing papers in PubMed.
- A New Genus and Species of Cochliopidae Tryon, 1866 (Truncatelloidea) from the Dominican Republic.Animals : an open access journal from MDPI · 2026Article
- UITOTO: a software for generating molecular diagnoses for species descriptions.Cladistics : the international journal of the Willi Hennig Society · 2026Article
- Cosmopolitan no more: Phylogenetics and reproductive mode reveal a global species complex in a marine mollusk (Teredinidae).PloS one · 2026Article
- Entirely Anatolian Hydrobiid (Caenogastropoda-Truncatelloidea-Hydrobiidae) Clade Revisited: Two More New Genera and Six New Species.Animals : an open access journal from MDPI · 2025Article
- Ocean Species Discoveries 13-27 - Taxonomic contributions to the diversity of Polychaeta, Mollusca and Crustacea.Biodiversity data journal · 2025Article
- Ocean Species Discoveries 1-12 - A primer for accelerating marine invertebrate taxonomy.Biodiversity data journal · 2024Article
- Tightening the requirements for species diagnoses would help integrate DNA-based descriptions in taxonomic practice.PLoS biology · 2023Article
- Article
- Describing the hidden species diversity ofZooKeys · 2021Article
- Trichite features contribute to the revision of the genus Strombidium (Alveolata, Ciliophora, Spirotricha).The Journal of eukaryotic microbiologyArticle
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6 authors.
Funding
Abstract
backgroundMolecular characters have been added in integrative taxonomic approaches in recent years. Nevertheless, taxon diagnoses are still widely restricted to morphological characters. The inclusion of molecular characters into taxon diagnoses is not only hampered by problems, such as their definition and the designation of their positions in a reference alignment, but also by the technical effort.
resultsDeSignate is a tool for character-based taxon diagnoses that includes a novel ranking scheme. It detects and classifies individual and combined signature characters (diagnostic molecular characters) based on so-called character state vectors. An intuitive web application guides the user through the analysis process and provides the results at a glance. Further, formal definitions and a uniform terminology of characters are introduced.
conclusionsDeSignate facilitates the inclusion of diagnostic molecular characters and their positions to complement taxon diagnoses. Compared to previous solutions, the tool simplifies the workflow and improves reproducibility and traceability of the results. The tool is freely available as a web application at (https://designate.dbresearch.uni-salzburg.at/) and is open source (https://github.com/DatabaseGroup/DeSignate/).
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