Evidence map›Paper›PMID 32312178›Full record

ArticleTissue engineering. Part A2020

Macrophage Effects on Mesenchymal Stem Cell Osteogenesis in a Three-Dimensional

Mónica Romero-López, Zhong Li, Claire Rhee, Masahiro Maruyama, Jukka Pajarinen, Benjamen O'Donnell, Tzu-Hua Lin, Chi-Wen Lo, John Hanlon, Rebecca Dubowitz and 5 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Tissue engineering. Part A, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
29citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

29 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Modeling Immunity In Vitro: Slices, Chips, and Engineered Tissues.Annual review of biomedical engineering · 2021
    Pooled it
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Review
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  10. 3D Culture of MSCs for Clinical Application.Bioengineering (Basel, Switzerland) · 2024
    Review
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  13. Article
  14. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Mónica Romero-LópezOrthopedic Research Laboratories, Department of Orthopaedic Surgery, Stanford University School of Medicine, Stanford, California, USA.
Zhong LiDepartment of Orthopedic Surgery, Center for Cellular and Molecular Engineering, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA.
Claire RheeOrthopedic Research Laboratories, Department of Orthopaedic Surgery, Stanford University School of Medicine, Stanford, California, USA.
Masahiro MaruyamaOrthopedic Research Laboratories, Department of Orthopaedic Surgery, Stanford University School of Medicine, Stanford, California, USA.
Jukka PajarinenOrthopedic Research Laboratories, Department of Orthopaedic Surgery, Stanford University School of Medicine, Stanford, California, USA.
Benjamen O'DonnellTulane Center for Stem Cell Research and Regenerative Medicine and Department of Pharmacology, Tulane University School of Medicine, New Orleans, Louisiana, USA.
Tzu-Hua LinOrthopedic Research Laboratories, Department of Orthopaedic Surgery, Stanford University School of Medicine, Stanford, California, USA.
Chi-Wen LoOrthopedic Research Laboratories, Department of Orthopaedic Surgery, Stanford University School of Medicine, Stanford, California, USA.
John HanlonOrthopedic Research Laboratories, Department of Orthopaedic Surgery, Stanford University School of Medicine, Stanford, California, USA.
Rebecca DubowitzOrthopedic Research Laboratories, Department of Orthopaedic Surgery, Stanford University School of Medicine, Stanford, California, USA.
Zhenyu YaoOrthopedic Research Laboratories, Department of Orthopaedic Surgery, Stanford University School of Medicine, Stanford, California, USA.
Bruce A BunnellTulane Center for Stem Cell Research and Regenerative Medicine and Department of Pharmacology, Tulane University School of Medicine, New Orleans, Louisiana, USA.
Hang LinDepartment of Orthopedic Surgery, Center for Cellular and Molecular Engineering, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA.
Rocky S TuanDepartment of Orthopedic Surgery, Center for Cellular and Molecular Engineering, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA.
Stuart B GoodmanOrthopedic Research Laboratories, Department of Orthopaedic Surgery, Stanford University School of Medicine, Stanford, California, USA.

Funding

Wear Particle Disease and NF-kappa B SignalingR01AR063717 · NIAMS · STANFORD UNIVERSITY · PI GOODMAN, STUART B · 2012 to 2021
$3.5M
Tissue Engineering Approaches for Improved Treatment of Early Stage Osteonecrosis of the HipR01AR072613 · NIAMS · STANFORD UNIVERSITY · PI GOODMAN, STUART B, YANG, YUNZHI · 2018 to 2022
$2.2M
Customized MSCs to Enhance Healing of Bone DefectsR01AR073145 · NIAMS · STANFORD UNIVERSITY · PI GOODMAN, STUART B · 2018 to 2021
$1.4M
NIAMS NIH HHS R01 AR063717NIAMS NIH HHS R01 AR072613NIAMS NIH HHS R01 AR073145
6 · The paper itself

Abstract

As musculoskeletal (MSK) disorders continue to increase globally, there is an increased need for novel,

Indexed as

Bone and BonesMesenchymal Stem CellsOsteogenesisAdultCell DifferentiationCells, CulturedHumansHydrogelsLeukocytes, MononuclearMacrophagesMaleTissue ScaffoldsYoung AdultHydrogelsbone healthhuman mesenchymal stem cellsmacrophagesmicrophysiological systemthree-dimensional culturetissue chip

Identifiers

PMID32312178
PMCPMC7580572

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.