Evidence map›Paper›PMID 32312045›Full record

ArticleLangmuir : the ACS journal of surfaces and colloids2020

Lipid Chemical Structure Modulates the Disruptive Effects of Nanomaterials on Membrane Models.

Saeed Nazemidashtarjandi, Amid Vahedi, Amir M Farnoud

Open access · greenAbstract read
In one paragraph

Article in Langmuir : the ACS journal of surfaces and colloids, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
0.8field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 16 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Saeed Nazemidashtarjandi
Amid Vahedi
Ohio University · US

Funding

Interactions of Engineered Nanomaterials with the Cell Plasma MembraneR15ES030140 · NIEHS · OHIO UNIVERSITY ATHENS · PI BURDICK, MONICA MAKI · 2019 to 2019
$429k
NIEHS NIH HHS R15 ES030140
6 · The paper itself

Abstract

Understanding the mechanisms by which engineered nanomaterials disrupt the cell plasma membrane is crucial in advancing the industrial and biomedical applications of nanotechnology. While the role of nanoparticle properties in inducing membrane damage has received significant attention, the role of the lipid chemical structure in regulating such interactions is less explored. Here, we investigated the role of the lipid chemical structure in the disruption of lipid vesicles by unmodified silica, carboxyl-modified silica, and unmodified polystyrene nanoparticles (50 nm). The role of the lipid headgroup was examined by comparing nanoparticle effects on vesicles composed of 1,2-dioleoyl-

Indexed as

NanoparticlesSphingomyelinsCell MembraneLipid BilayersPhosphatidylcholinesPolystyrenesLipid BilayersPhosphatidylcholinesPolystyrenesSphingomyelins

Identifiers

PMID32312045
PMCPMC8725912
OpenAlexW3016511734

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.