Evidence map›Paper›PMID 32312007›Full record

ArticleMedicine2020

Fine-needle aspiration with rapid parathyroid hormone assay to identify parathyroid gland in thyroidectomy.

Xian Zou, Longshun Shi, Guohua Zhu, Liguo Zhu, Jiandong Bao, Jun Fan, Yonghong Hu, Bin Zhou, Zhongwei Lv

Open access · goldAbstract readComparative Study
In one paragraph

Article in Medicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.0field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 8 citations in OpenAlex.

  1. Review
  2. Review
  3. [Research progress of autofluorescence imaging of parathyroid glands].Lin chuang er bi yan hou tou jing wai ke za zhi = Journal of clinical otorhinolaryngology head and neck surgery · 2022
    Review
  4. Article
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 2 countries.

Xian ZouJiangyuan Hospital Affiliated to Jiangsu Institute of Nuclear Medicine.
Longshun ShiKey Laboratory of Nuclear Medicine, Ministry of Health, Jiangsu Key Laboratory of Molecular Nuclear Medicine, Jiangsu Institute of Nuclear Medicine, Wuxi, Jiangsu.
Guohua ZhuJiangyuan Hospital Affiliated to Jiangsu Institute of Nuclear Medicine.
Liguo ZhuJiangyuan Hospital Affiliated to Jiangsu Institute of Nuclear Medicine.
Jiandong BaoJiangyuan Hospital Affiliated to Jiangsu Institute of Nuclear Medicine.
Jun FanKey Laboratory of Nuclear Medicine, Ministry of Health, Jiangsu Key Laboratory of Molecular Nuclear Medicine, Jiangsu Institute of Nuclear Medicine, Wuxi, Jiangsu.
Yonghong HuThe Synergetic Innovation Center for Advanced Materials, State Key Laboratory of Materials-Oriented Chemical Engineering, College of Biotechnology and Pharmaceutical Engineering, Nanjing Tech University, Nanjing.
Bin ZhouKey Laboratory of Nuclear Medicine, Ministry of Health, Jiangsu Key Laboratory of Molecular Nuclear Medicine, Jiangsu Institute of Nuclear Medicine, Wuxi, Jiangsu.
Zhongwei LvDepartment of Nuclear Medicine, Shanghai 10th People's Hospital, Tongji University School of Medicine, Shanghai, China.
Ministry Of Health · FJThe Synergetic Innovation Center for Advanced Materials · CNTongji University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

To determine the levels of parathyroid hormone (PTH) in the fluids of various tissues for identification of parathyroid glands during thyroidectomy.Our study comprised 31 patients with thyroid cancer who underwent lobectomy with central compartment dissection at our hospital from October 2014 to February 2015. A total of 186 tissue samples, including 28 from parathyroid glands and 158 from non-parathyroid tissues, were obtained during the operations. Tissue fluids were collected via fine-needle aspiration to measure PTH levels; the tissue was punctured 3 times with a 26-gauge syringe needle and washed with 0.5 mL normal saline. Tissues were also prepared for pathological examination.PTH concentrations were significantly higher in parathyroid tissues than non-parathyroid tissues. None of the patients had irremediable parathyroid dysfunction after surgical resection.Use of fine-needle aspiration for quantification of PTH levels in tissue fluids rapidly, safely, and effectively identifies the parathyroid glands during thyroidectomy.

Indexed as

AdultAgedBiopsy, Fine-NeedleFemaleHumansHypothyroidismLymph Node ExcisionMaleMiddle AgedMonitoring, IntraoperativeParathyroid DiseasesParathyroid GlandsParathyroid HormonePostoperative PeriodSensitivity and SpecificityThyroidectomyParathyroid Hormone

Identifiers

PMID32312007
PMCPMC7220132
OpenAlexW3016452788

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.