ArticleMedicine2020
Prevalence of osteoporosis in patients with type 2 diabetes mellitus in the Chinese mainland: A protocol of systematic review and meta-analysis.
Article in Medicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers, 1 of them a synthesis that pooled it.
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Who cites it
27 citing papers in PubMed, 1 synthesis or guideline pooled it, 44 citations in OpenAlex.
- The lead and cadmium content in rice and risk to human health in China: A systematic review and meta-analysis.PloS one · 2022Pooled it
- Sex differences in the association between bone mineral density and lipid profiles in people with type 2 diabetes in southwest China.Metabolism open · 2026Article
- Serum CTRP3 and CysC correlate with glucose, lipid, and bone metabolism in elderly patients with type 2 diabetes mellitus complicated with osteoporosis.Journal of diabetes investigation · 2026Article
- The clinical evaluation value of the NRF2-mediated antioxidant stress mechanism in elderly patients with type 2 diabetes mellitus complicated by osteoporosis.Journal of medical biochemistry · 2026Article
- Clinical features of osteoporosis in patients with type 1 and type 2 diabetes in Türkiye: A nationwide study.Archives of osteoporosis · 2026Article
- Development and validation of a multimodal interpretable machine learning model for the identification of osteoporosis in patients with type 2 diabetes mellitus: a multicenter retrospective study.Frontiers in endocrinology · 2026Article
- A high FT3 level might protect bone mineral density among euthyroid type 2 diabetes mellitus patients.Endocrine connections · 2025Article
- Epimedium brevicornum Maxim alleviates diabetes osteoporosis by regulating AGE-RAGE signaling pathway.Molecular medicine (Cambridge, Mass.) · 2025Article
- Use of GLP-1 receptor agonist and risk of osteoporosis among patients with type 2 diabetes: a real-world study.Frontiers in endocrinology · 2025Article
- Exosome-basedRegenerative biomaterials · 2025Article
- Albumin: a mediator of the association between serum calcium and triglyceride-glucose index among Chinese individuals with osteoporotic fractures.Frontiers in endocrinology · 2025Article
- Development and validation of an explainable machine learning model for predicting osteoporosis in patients with type 2 diabetes mellitus.Frontiers in endocrinology · 2025Article
- The correlation between TyG-BMI and the risk of osteoporosis in middle-aged and elderly patients with type 2 diabetes mellitus.Frontiers in nutrition · 2025Article
- Correlation between bone mineral density and type 2 diabetes mellitus in elderly men and postmenopausal women.Scientific reports · 2024Article
- Links among Obesity, Type 2 Diabetes Mellitus, and Osteoporosis: Bone as a Target.International journal of molecular sciences · 2024Review
- Acid sphingomyelinase mediates ferroptosis induced by high glucose via autophagic degradation of GPX4 in type 2 diabetic osteoporosis.Molecular medicine (Cambridge, Mass.) · 2023Article
- Assessment of osteoporosis in patients with type 2 diabetes mellitus: A study from the central region of Saudi Arabia.Saudi medical journal · 2023Article
- Type 2 diabetes mellitus plays a protective role against osteoporosis --mendelian randomization analysis.BMC musculoskeletal disorders · 2023Article
- P53 negatively regulates the osteogenic differentiation in jaw bone marrow MSCs derived from diabetic osteoporosis.Heliyon · 2023Article
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Authors and funding
5 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundOsteoporosis, as a metabolic disease, has become one of the most rapidly growing complications of diabetes mellitus. Previously, we conducted a systematic review to report the estimated prevalence of osteoporosis among patients with type 2 diabetes mellitus (T2DM) from 2001 to 2016. However, some newer studies have been reported, and more potential risk factors for osteoporosis remain controversial and vague. Therefore, the presented review is tailored to synthesize available evidence regarding the pooled prevalence and related risk factors of osteoporosis among T2DM patients in mainland China.
methodsBoth cross-sectional study and cohort study reporting on the prevalence of osteoporosis among patients with T2DM in mainland China, published in Chinese or English, will be considered for inclusion. Records from 4 English databases and 2 Chinese databases will be retrieved from their inceptions to March 2020. The process of study selection, data extraction, and methodologic quality assessment will be independently executed by 2 reviewers. The pooled prevalence of osteoporosis and the prevalence in the exposed and unexposed groups for each potential risk factor will be calculated by the software Stata version 12.0.
resultsThe current systematic review and meta-analysis will provide more precise prevalence rates and associated risk factors of osteoporosis among people with T2DM in mainland China.
conclusionThe study will offer high-quality and explicit evidence for assisting diabetic patients to prevent osteoporosis in mainland China. OSF REGISTRATION: DOI 10.17605/OSF.IO/5ZKJ6.
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