SynthesisMedicine2020
Association between red cell distribution width level and risk of stroke: A systematic review and meta-analysis of prospective studies.
Synthesis in Medicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
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Who cites it
11 citing papers in PubMed.
- Article
- Association between admission hemoglobin-to-red blood cell distribution width ratio and stroke-associated pneumonia risk in acute ischemic stroke: effect modification by diabetes status.Frontiers in endocrinology · 2026Article
- Insights of red cell distribution width for mortality in septic patients with diabetes mellitus: A multicenter cohort study.PloS one · 2025Article
- Predictive value of red cell distribution width for overlap syndrome in obstructive sleep apnea.Frontiers in neurology · 2024Article
- Association between red cell distribution width-to-platelet ratio and short-term and long-term mortality risk in patients with acute ischemic stroke.BMC neurology · 2023Article
- Red cell distribution width as a prognosticator in patients with heart failure.ESC heart failure · 2023Article
- Article
- Red Cell Distribution Width Is Independently Associated with Mortality in Sepsis.Medical principles and practice : international journal of the Kuwait University, Health Science Centre · 2022Article
- Article
- Article
- Observational
Corrections and comments
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Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundRed cell distribution width level may have relations with the incidence and prognosis of cerebrovascular diseases. Recent researches have reported that red cell distribution width level was linked to the occurrence of stroke. However, the predicted effect of red cell distribution width in stroke is still disputed. We sought to assess the relationship between red cell distribution width and risk of stroke in this meta-analysis.
methodsRelevant studies were picked out from the databases of Embase, PubMed, and Cochrane Library. Hazard ratio with 95% confidence interval was chosen to analyze each trial, which was extracted from results of the highest and lowest red cell distribution width group. Funnel plots, Begg and Egger test were used to assess publication bias in the meta-analysis. Stata(12.0) was utilized to perform statistic analysis in the process.
resultsA total of 6 studies with 5783 patients were included in this meta-analysis. The results showed that red cell distribution width level in patients with stroke was significantly higher than it in those without stroke (HR = 1.34, 95%CI:1.23-1.47, P < .001), in particular ischemic stroke(HR = 1.34,95% confidence interval:1.1-1.54, P < .001). There was no evidence of heterogeneity across the studies (P = .355, I = 5.53%).
conclusionsThe higher red cell distribution width level was associated with an increased risk of stroke, especially ischemic infarction.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.