Evidence map›Paper›PMID 32311866›Full record

ArticleAnnals of coloproctology2020

Early and Late Functional Outcomes of Anal Sphincter-Sparing Procedures With Total Mesorectal Excision for Anorectal Adenocarcinoma

Osama Eldamshety, Sherif Kotb, Ashraf Khater, Sameh Roshdy, Mohamed Elashry, Mohamed S Zahi, Hend M Hamdey Rashed Elkalla, Waleed Elnahas, Omar Farouk, Adel Fathi and 7 more

Open access · goldAbstract read
In one paragraph

Article in Annals of coloproctology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 1 pooled it
1.3field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 1 synthesis or guideline pooled it, 17 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Review
  6. Review
  7. Review
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors at 2 institutions in 2 countries.

Osama Eldamshetysurgical oncology, oncology centre, Mansoura university, Elmansoura, Egypt.
Sherif KotbSurgery department, Oncology Centre of Mansoura University, Mansoura, Egypt.
Ashraf KhaterSurgery department, Oncology Centre of Mansoura University, Mansoura, Egypt.
Sameh RoshdySurgery department, Oncology Centre of Mansoura University, Mansoura, Egypt.
Mohamed ElashryDepartment of clinical oncology and nuclear medicine, Mansoura University, Mansoura, Mansoura, Egypt.
Mohamed S ZahiDepartment of clinical oncology and nuclear medicine, Mansoura University, Mansoura, Mansoura, Egypt.
Hend M Hamdey Rashed ElkallaDepartment of clinical oncology and nuclear medicine, Mansoura University, Mansoura, Mansoura, Egypt.
Waleed ElnahasSurgery department, Oncology Centre of Mansoura University, Mansoura, Egypt.
Omar FaroukSurgery department, Oncology Centre of Mansoura University, Mansoura, Egypt.
Adel FathiSurgery department, Oncology Centre of Mansoura University, Mansoura, Egypt.
Ahmed SenbelSurgery department, Oncology Centre of Mansoura University, Mansoura, Egypt.
Emad-Eldeen HamedSurgery department, Oncology Centre of Mansoura University, Mansoura, Egypt.
Khaled AbdelwahabSurgery department, Oncology Centre of Mansoura University, Mansoura, Egypt.
Islam Abdou ElzahbySurgery department, Oncology Centre of Mansoura University, Mansoura, Egypt.
Ahmed AbdallahSurgery department, Oncology Centre of Mansoura University, Mansoura, Egypt.
Mahmoud AbdelazizSurgery department, Oncology Centre of Mansoura University, Mansoura, Egypt.
Emanuele LezocheSurgery department, Policlinico Umberto primo, Sapienza University of Rome, Rome, Italy.
Mansoura University · EGPoliclinico Umberto I · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe study aims to assess the functional outcome of anal sphincter sparing procedures (SSP) with TME for anorectal adenocarcinoma.

methodsIn a multicentric, prospective, single-group study in the period between December 2012 and November 2017, 93 patients presented with anorectal adenocarcinoma were included in the study. Sixty-nine patients underwent SSP with TME. SSP included the combined approach of transabdominal TME with intersphincteric resection (ISR) or transanal transabdominal TME (TATA). Using the Per Anal Examination Scoring System (PASS), postoperative anal function was assessed after one year.

resultsBowel motility time was 50 (±19) hours. The time needed for narcotic analgesia was 54 (±18.8) hours. Mean hospital stay was 15.4 (±10.25) days. Incidence of evident fecal incontinence after ISR is 10.6% (7/67 cases). The Per Anal Examination Scoring System (PASS) findings of 69 cases are as follows: extremely hypotonic 8.6% (6 cases), slightly hypotonic 26.1% (18 cases), normal tone 58% (40 cases), slightly stenotic 3 cases (4.3%), or occluded 2.9% (2 cases). Urinary dysfunction occurred in one case (1.4%). Temporary diversion was performed in 61 patients (87.1%).

conclusionSphincter preservation with TME for anorectal adenocarcinoma helps avoid permanent stoma and provides a reasonable functional outcome. PASS is a new application for postoperative assessment of anal function.

Indexed as

anal sphincter preservationanorectal adenocarcinomapostoperative continenceTotal mesorectal excisionvery low rectal cancer

Identifiers

PMID32311866
PMCPMC7392569
OpenAlexW3016898446

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.