ArticleMicrobial pathogenesis2020
Etiology and genetic evolution of canine coronavirus circulating in five provinces of China, during 2018-2019.
Article in Microbial pathogenesis, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers, 1 of them a synthesis that pooled it.
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Who cites it
27 citing papers in PubMed, 1 synthesis or guideline pooled it.
- A systematic review and meta-analysis of canine enteric coronavirus prevalence in dogs of mainland China.Virology journal · 2024Pooled it
- Cross-Species Transmission and Recombination Between Feline and Canine Coronaviruses in Jiangsu-Zhejiang Region in 2025.Veterinary sciences · 2026Article
- Genetic characterization and structural insights of canine astroviruses circulating in South Korea.BMC veterinary research · 2026Article
- First report on detection and molecular characterization of alphacoronaviruses in the small Indian mongoose (Urva auropunctata).Virology journal · 2025Article
- First Molecular Insights into the Presence of Canine Kobuvirus in Ecuadorian Dogs Through the Standardization of a Sensitive SYBR Green RT-qPCR Assay.Veterinary sciences · 2025Article
- Review
- Linking Pollution and Viral Risk: Detection of Dioxins and Coronaviruses in Cats and Dogs.Viruses · 2025Article
- Circulation and Genetic Characterizations of Coronaviruses From Companion Animals in Chengdu, Southwest China: One-Year Postpandemic.Transboundary and emerging diseases · 2025Article
- Genetic and Evolutionary Analysis of Canine Coronavirus in Guangxi Province, China, for 2021-2024.Veterinary sciences · 2024Article
- Genetic tracing of market wildlife and viruses at the epicenter of the COVID-19 pandemic.Cell · 2024Article
- First Report on the Molecular Detection of Canine Astrovirus (CaAstV) in Dogs with Gastrointestinal Disease in Ecuador Using a Fast and Sensitive RT-qPCR Assay Based on SYBR GreenVeterinary sciences · 2024Article
- Molecular characterization and lineage analysis of canine astrovirus strains from dogs with gastrointestinal disease in Ecuador based on ORF-2 gene analysis.Frontiers in veterinary science · 2024Article
- A narrative review of alternative transmission routes of COVID 19: what we know so far.Pathogens and global health · 2023Review
- A One Health Perspective on Canine Coronavirus: A Wolf in Sheep's Clothing?Microorganisms · 2023Review
- Epidemiology and Molecular Characterizations of Coronavirus from Companion Animals Living in Chengdu, Southwest China.Transboundary and emerging diseases · 2023Article
- Isolation of a Novel Recombinant Canine Coronavirus From a Visitor to Haiti: Further Evidence of Transmission of Coronaviruses of Zoonotic Origin to Humans.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2022Article
- Review
- Identification of a canine coronavirus in Australian racing Greyhounds.Journal of veterinary diagnostic investigation : official publication of the American Association of Veterinary Laboratory Diagnosticians, Inc · 2022Article
- Characterization of the VP2 and NS1 genes from canine parvovirus type 2 (CPV-2) and feline panleukopenia virus (FPV) in Northern China.Frontiers in veterinary science · 2022Article
- Detection and Molecular Characterization of Canine Alphacoronavirus in Free-Roaming Dogs, Bangladesh.Viruses · 2021Article
Corrections and comments
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Authors and funding
11 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
As the outbreaks of COVID-19 in worldwide, coronavirus has once again caught the attention of people. Canine coronavirus is widespread among dog population, and sometimes causes even fatal cases. Here, to characterize the prevalence and evolution of current circulating canine coronavirus (CCoV) strains in China, we collected 213 fecal samples from diarrheic pet dogs between 2018 and 2019. Of the 213 samples, we found 51 (23.94%) were positive for CCoV. Co-infection with canine parvovirus (CPV), canine astrovirus (CaAstV), canine kobuvirus (CaKV), Torque teno canis virus (TTCaV) were ubiquitous existed. Mixed infection of different CCoV subtypes exists extensively. Considering the limited sequences data in recent years, we sequenced 7 nearly complete genomes and 10 complete spike gene. Phylogenetic analysis of spike gene revealed a new subtype CCoV-II Variant and CCoV-IIa was the most prevalent subtype currently circulating. Moreover, we identified strain B906_ZJ_2019 shared 93.24% nucleotide identifies with previous strain A76, and both of them clustered with CCoV-II Variant, which were not well clustered with the known subtypes. Recombination analysis of B906_ZJ_2019 indicated that strain B906_ZJ_2019 may a recombinant variant between CCoV-I and CCoV-II, which is consistent with strain A76. Furthermore, amino acid variations widely existed among current CCoV-IIa strains circulating in China and the classic CCoV-IIa strains, in spite of the unknown functions. In a word, we report a useful information as to the etiology and evolution of canine coronavirus in China based on the available sequences, which is urgent for the devise of future effective disease prevention and control strategies.
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