Evidence map›Paper›PMID 32311350›Full record

SynthesisAmerican journal of obstetrics and gynecology2020

Coronavirus disease 2019 during pregnancy: a systematic review of reported cases.

Anna Nunzia Della Gatta, Roberta Rizzo, Gianluigi Pilu, Giuliana Simonazzi

2 registry-linked trialsOpen access · bronzeAbstract readSystematic ReviewVideo-Audio Media
In one paragraph

Synthesis in American journal of obstetrics and gynecology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 172 papers, 37 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
172citing papers in PubMed, 37 pooled it
28.6field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04563065 naunknown statusnot on this map

Active Pregnancy, Prevention Against the Effects of COVID-19

TypeinterventionalSponsorUniversidad Politecnica de MadridRan2020 to 2023Enrolled280ConditionsPregnancy Complications, Pregnancy, High Risk, Pregnancy Induced Hypertension, Newborn MorbidityArmsExercise program, Healthy lifestyle advise
NCT04598347 unknown statusnot on this map

Valuation of the Possible Vertical Transmission of SARS-CoV-2 Through Study of Amniotic Fluid and Chorionic Villi of Affected Pregnant Women for the COVID-19

Typeobservational_patient_registrySponsorFundació Institut de Recerca de l'Hospital de la Santa Creu i Sant PauRan2020 to 2022Enrolled225ConditionsCovid19, Pregnancy Related
3 · Its place in the literature

Who cites it

172 citing papers in PubMed, 37 syntheses or guidelines pooled it, 329 citations in OpenAlex.

  1. Pooled it
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  3. The spectrum of movement disorders in neurosyphilis: A systematic review.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2026
    Pooled it
  4. Movement Disorders in Scrub Typhus: A Systematic Review.Tremor and other hyperkinetic movements (New York, N.Y.) · 2026
    Pooled it
  5. Spectrum of movement disorders in Malaria: a systematic review of case reports, case series, and cohort studies.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2025
    Pooled it
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  8. Movement Disorders in Neurocysticercosis: A Systematic Review.Tremor and other hyperkinetic movements (New York, N.Y.) · 2025
    Pooled it
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  10. Movement Disorders in Toxoplasmosis: A Systematic Review.Tremor and other hyperkinetic movements (New York, N.Y.) · 2025
    Pooled it
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  12. Clinical features, pathogenesis, pathology, neuroimaging, clinical course and outcome of measles inclusion-body encephalitis: a systematic review of published case reports and case series.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2024
    Pooled it
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  14. The etiological spectrum of multiple ring-enhancing lesions of the brain: a systematic review of published cases and case series.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2024
    Pooled it
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  19. Clinical and Obstetric Aspects of Pregnant Women with COVID-19: A Systematic Review.Revista brasileira de ginecologia e obstetricia : revista da Federacao Brasileira das Sociedades de Ginecologia e Obstetricia · 2021
    Pooled it
  20. Pooled it

112 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Anna Nunzia Della GattaObstetric Unit, Department of Medical and Surgical Sciences, Policlinico Sant'Orsola-Malpighi, University of Bologna, Bologna, Italy. Electronic address: anna.dellagatta2@unibo.it.
Roberta RizzoObstetric Unit, Department of Medical and Surgical Sciences, Policlinico Sant'Orsola-Malpighi, University of Bologna, Bologna, Italy.
Gianluigi PiluObstetric Unit, Department of Medical and Surgical Sciences, Policlinico Sant'Orsola-Malpighi, University of Bologna, Bologna, Italy.
Giuliana SimonazziObstetric Unit, Department of Medical and Surgical Sciences, Policlinico Sant'Orsola-Malpighi, University of Bologna, Bologna, Italy.
Policlinico S.Orsola-Malpighi · ITUniversity of Bologna · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveThis study aimed to conduct a systematic review of the clinical outcomes reported for pregnant patients with coronavirus disease 2019. DATA SOURCES: The PubMed, CINAHL, and Scopus databases were searched using a combination of key words such as "Coronavirus and/or pregnancy," "COVID and/or pregnancy," "COVID disease and/or pregnancy," and "COVID pneumonia and/or pregnancy." There was no restriction of language to allow collection of as many cases as possible. STUDY ELIGIBILITY CRITERIA: All studies of pregnant women who received a coronavirus disease 2019 diagnosis using acid nucleic test, with reported data about pregnancy, and, in case of delivery, reported outcomes, were included. STUDY APPRAISAL AND SYNTHESIS

methodsAll the studies included have been evaluated according to the tool for evaluating the methodological quality of case reports and case series described by Murad et al.

resultsSix studies that involved 51 pregnant women were eligible for the systematic review. At the time of the report, 3 pregnancies were ongoing; of the remaining 48 pregnant women, 46 gave birth by cesarean delivery, and 2 gave birth vaginally; in this study, 1 stillbirth and 1 neonatal death were reported.

conclusionAlthough vertical transmission of severe acute respiratory syndrome coronavirus 2 infection has been excluded thus far and the outcome for mothers and neonates has been generally good, the high rate of preterm delivery by cesarean delivery is a reason for concern. Cesarean delivery was typically an elective surgical intervention, and it is reasonable to question whether cesarean delivery for pregnant patients with coronavirus disease 2019 was warranted. Coronavirus disease 2019 associated with respiratory insufficiency in late pregnancies certainly creates a complex clinical scenario.

Indexed as

AdultBetacoronavirusCesarean SectionCoronavirus InfectionsCOVID-19FemaleHumansInfant, NewbornInfectious Disease Transmission, VerticalPandemicsPneumonia, ViralPregnancyPregnancy Complications, InfectiousPregnancy OutcomeSARS-CoV-2cesarean deliverycoronavirus pneumoniaCOVID-19fetal deathneonatal outcomespreterm birthSARS-CoV-2stillbirthvertical transmission novel coronavirusviral pneumonia

Identifiers

PMID32311350
PMCPMC7165087
OpenAlexW3016273932

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.