Evidence map›Paper›PMID 32311088›Full record

ArticleBritish journal of haematology2020

Deficit of circulating CD19

Yoshitaka Zaimoku, Bhavisha A Patel, Sachiko Kajigaya, Xingmin Feng, Lemlem Alemu, Diego Quinones Raffo, Emma M Groarke, Neal S Young

Open access · bronzeAbstract read
In one paragraph

Article in British journal of haematology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed
1.8field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 34 citations in OpenAlex.

  1. Article
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  12. Influence of Housing Temperature and Genetic Diversity on Allogeneic T Cell-Induced Tissue Damage in Mice.Pathophysiology : the official journal of the International Society for Pathophysiology · 2023
    Article
  13. Review
  14. Article
  15. Article
  16. Post-therapy B Regulatory Cells Might early Predict Relapse in Hodgkin Lymphoma.Mediterranean journal of hematology and infectious diseases · 2022
    Article
  17. Article
  18. Review
  19. Article
  20. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Yoshitaka ZaimokuHematology Branch, National Heart, Lung, and Blood Institute, NIH, Bethesda, MD, USA.ORCID 0000-0002-4108-5245
Bhavisha A PatelHematology Branch, National Heart, Lung, and Blood Institute, NIH, Bethesda, MD, USA.
Sachiko KajigayaHematology Branch, National Heart, Lung, and Blood Institute, NIH, Bethesda, MD, USA.
Xingmin FengHematology Branch, National Heart, Lung, and Blood Institute, NIH, Bethesda, MD, USA.
Lemlem AlemuHematology Branch, National Heart, Lung, and Blood Institute, NIH, Bethesda, MD, USA.
Diego Quinones RaffoHematology Branch, National Heart, Lung, and Blood Institute, NIH, Bethesda, MD, USA.
Emma M GroarkeHematology Branch, National Heart, Lung, and Blood Institute, NIH, Bethesda, MD, USA.
Neal S YoungHematology Branch, National Heart, Lung, and Blood Institute, NIH, Bethesda, MD, USA.
National Heart Lung and Blood Institute · US

Funding

Pathogenesis And Treatment Of Aplastic AnemiaZIAHL002315 · NHLBI · NATIONAL HEART, LUNG, AND BLOOD INSTITUTE · PI YOUNG, NEAL S · 2009 to 2025
$60.1M
Intramural NIH HHS ZIA HL002315NHLBI NIH HHS
6 · The paper itself

Abstract

Immune aplastic anaemia (AA) is caused by cytotoxic T lymphocytes (CTLs) that destroy haematopoietic stem and progenitor cells. Enhanced type 1 T helper (Th1) responses and reduced regulatory T cells (Tregs) are involved in the immune pathophysiology. CD24

Indexed as

AdolescentADP-ribosyl Cyclase 1AdultAgedAnemia, AplasticAntigens, CD19Antilymphocyte SerumBenzoatesB-Lymphocytes, RegulatoryB-Lymphocyte SubsetsBone MarrowCD24 AntigenCD4-Positive T-LymphocytesCD8-Positive T-LymphocytesCyclosporineFemaleADP-ribosyl Cyclase 1Antigens, CD19Antilymphocyte SerumBenzoatesCD19 molecule, humanCD24 AntigenCD24 protein, humanCD38 protein, humanCyclosporineeltrombopagHydrazinesIL10 protein, humanImmunosuppressive AgentsInterleukin-10Membrane GlycoproteinsMPL protein, humanPyrazolesReceptors, Thrombopoietinaplastic anaemiaflow cytometryimmunosuppressive therapylymphocyte subsetsregulatory B cells

Identifiers

PMID32311088
PMCPMC7496711
OpenAlexW3017021144

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.