Evidence map›Paper›PMID 32310981›Full record

ArticlePloS one2020

Swelling characteristics and biocompatibility of ionic liquid based hydrogels for biomedical applications.

Johanna Claus, Andreas Brietzke, Celina Lehnert, Stefan Oschatz, Niels Grabow, Udo Kragl

Abstract read
In one paragraph

Article in PloS one, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed.

  1. Dendrimers-based Hydrogels and Nanogels for Drug Delivery.Current pharmaceutical biotechnology · 2026
    Review
  2. Review
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Review
  9. Review
  10. Article
  11. Article
  12. Ionic Liquid-Based Materials for Biomedical Applications.Nanomaterials (Basel, Switzerland) · 2021
    Review
  13. Article
  14. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Johanna ClausDepartment of Chemistry, Industrial and Applied Chemistry, University of Rostock, Rostock, Germany.ORCID 0000-0003-2557-4425
Andreas BrietzkeInstitute for Biomedical Engineering, Rostock University Medical Center, Rostock, Germany.
Celina LehnertDepartment of Chemistry, Industrial and Applied Chemistry, University of Rostock, Rostock, Germany.
Stefan OschatzInstitute for Biomedical Engineering, Rostock University Medical Center, Rostock, Germany.
Niels GrabowDepartment Life, Light and Matter, University of Rostock, Rostock, Germany.
Udo KraglDepartment of Chemistry, Industrial and Applied Chemistry, University of Rostock, Rostock, Germany.ORCID 0000-0002-2507-7472

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Polymers are commonly used in medical device manufacturing, e.g. for drug delivery systems, bone substitutes and stent coatings. Especially hydrogels exhibit very promising properties in this field. Hence, the development of new hydrogel systems for customized application is of great interest, especially regarding the swelling behavior and mechanical properties as well as the biocompatibility. The aim of this work was the preparation and investigation of various polyelectrolyte and poly-ionic liquid based hydrogels accessible by radical polymerization. The obtained polymers were covalently crosslinked with N,N'-methylenebisacrylamide (MBAA) or different lengths of poly(ethyleneglycol)diacrylate (PEGDA). The effect of different crosslinker-to-monomer ratios has been examined. In addition to the compression curves and the maximum degree of swelling, the biocompatibility with L929 mouse fibroblasts of these materials was determined in direct cell seeding experiments and the outcome for the different hydrogels was compared.

Indexed as

AcrylamidesAnimalsBiocompatible MaterialsCell LineCell SurvivalCompressive StrengthHydrogelsIonic LiquidsMicePolyethylene GlycolsAcrylamidesBiocompatible MaterialsHydrogelsIonic LiquidsN,N'-methylenebisacrylamidepoly(ethylene glycol)diacrylatePolyethylene Glycols

Identifiers

PMID32310981
PMCPMC7170238

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.